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Friday, Nov 17th
2:50 PM – 3:00 PM PT
DDEL-06 - Microglia repair the disrupted blood-brain barrier following low-intensity pulsed ultrasound through P2RY12 signaling
Location: Exhibit Hall C
Plenary Abstract Presenter: Karl Habashy – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Victor A. Arrieta – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Yu Luan – Northwestern University
Author: Kwang-Soo Kim – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Silpol Dhiantravan – Northwestern University
Author: Hinda Najem – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Mateo Gomez – Northwestern University
Author: Crismita Dmello – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Li Chen – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Ruth Saganty – Northwestern University
Author: Andrew Gould – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Ye Hou – Northwestern University
Author: Amy B. Heimberger – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
Author: Michael Canney – Carthera
Author: Roger Stupp – Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Author: Feng Yue – Northwestern University
Author: Adam M. Sonabend – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Drug delivery
Friday, Nov 17th
3:45 PM – 3:55 PM PT
DDEL-12 - A conformable implantable device - microMESH - for the sustained delivery of chemotherapeutic molecules and immune check point inhibitors against high-grade gliomas
Location: Room 118-120
Author: Anna Lisa Palange – Italian Institute of Technology
Author: Irene Guerriero – Italian Institute of Technology
Author: Cristiano Pesce – Italian Institute of Technology
Author: Daniele Di Mascolo – Italian Institute of Technology
Oral Abstract Presenter: Paolo Decuzzi – Italian Institute of Technology
Drug delivery
Friday, Nov 17th
3:55 PM – 4:05 PM PT
DDEL-04 - Modulation of the blood-tumor barrier for improved drug delivery in glioblastoma
Location: Room 118-120
Author: Jorge-Luis Jimenez-Macias – Brown University
Author: Zheyun Xu – Brown University
Author: Doug Anthony – Brown University
Author: Alex Brodsky – Brown University
Author: George Tollefson – Brown University
Author: William Hawkins – Brown University
Author: Andrea Schmidt – Brown University
Author: Michael Sun – Brown University
Author: Jason Hong – Brown University
Author: Megan Forrest – Brown University
Author: Michal Nowicki – Brigham and Women's Hospital/ Harvard Medical School
Author: Paul Bertone – Brown University
Oral Abstract Presenter: Sean E. Lawler – Dept of Pathology and Laboratory Medicine, Legorreta Cancer Center, Brown University
Drug delivery
Friday, Nov 17th
4:25 PM – 4:35 PM PT
DDEL-13 - Cilia Inhibitors Synergize with Temozolomide to Dramatically Improve Survival in Orthotopic Murine Models of Glioblastoma
Location: Room 118-120
Oral Abstract Presenter: Benjamin J. Umlauf – University of Texas at Austin
Drug delivery
Friday, Nov 17th
4:45 PM – 4:50 PM PT
DDEL-03 - Physiologically based pharmacokinetic (PBPK) modeling of heterogeneous drug penetration into the human brain and glioblastoma
Location: Room 118-120
Oral Abstract Presenter: Jing Li – Karmanos Cancer Institute, Wayne State University
Author: Nader Sanai – Barrow Neurological Institute
Author: Artak Tovmasyan – Barrow Neurological Institute
Author: Seongho Kim – Karmanos Cancer Institute
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-01 - Utilizing sensor arrays for intracranial pressure (ICP) response to cerebrospinal fluid (CSF) drug administration, and potential implications for personalized care in CNS metastases patients.
Location: Exhibit Hall A/B
Poster Presenter: Nisheka N. Vanjani – Northwestern University Feinberg School of Medicine
Author: Rajan Patel – EnClear Therapies
Author: Marcie A. Glicksman – EnClear Therapies
Author: Nathan Moelis – EnClear Therapies
Author: Grace Y. Lee – Northwestern University Feinberg School of Medicine
Author: Priya U. Kumthekar – Northwestern University
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-02 - Clinical Benefit of Bevacizumab and Irinotecan (BEV+IRI) in Patients With Relapsed/Refractory Glioblastoma (r/rGBM) and its Potential Predictors
Location: Exhibit Hall A/B
Author: Ji Hyun Park – konkuk medical center
Poster Presenter: Kyung Rae Cho – Konkuk medical center
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-05 - Pharmacokinetic assessment of convection-enhanced delivery of small molecule drugs for H3 K27-altered diffuse midline glioma
Location: Exhibit Hall A/B
Poster Presenter: Julian S. Rechberger – Mayo Clinic Rochester
Author: Jacob B. Anderson – Mayo Clinic Rochester
Author: Jizhi Ge – Mayo Clinic Rochester
Author: Liang Zhang – Nanostring
Author: David J. Daniels – Mayo Clinic Rochester
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-08 - The Ommaya in leptomeningeal disease and central nervous system malignancies: a reservoir of the past or source of the future?
Location: Exhibit Hall A/B
Author: Eris Spirollari – New York Medical College
Author: Sima Vazquez – New York Medical College
Author: Daniel Durkin – New York Medical College
Author: Jacob Fliegelman – New York Medical College
Author: Austin Carpenter – Westchester Medical Center
Author: Jose Dominguez – Westchester Medical Center
Poster Presenter: Simon Hanft – Westchester Medical Center
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-09 - Saturated fatty acid emulsion opens the blood-brain barriers and enhances drug delivery
Location: Exhibit Hall A/B
Poster Presenter: Kyoung Su Sung – Department of Neurosurgery, Dong-A University Hospital, Dong-A University College of Medicine
Author: Won-Ho Cho – Pusan National Univeristy Hospital
Author: Hak Jin Kim – Pusan National Univeristy Hospital
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-10 - Retrospective review of intra-CSF drug delivery: safety and drug distribution profiles of intracerebroventricular (ICV), lumbar intrathecal (LIT), and intra-cisterna magna (ICM) injections
Location: Exhibit Hall A/B
Poster Presenter: Grace Y. Lee – Northwestern University Feinberg School of Medicine
Author: Marcie A. Glicksman – EnClear Therapies
Author: Rajan Patel – EnClear Therapies
Author: Nisheka N. Vanjani – Northwestern University Feinberg School of Medicine
Author: Priya U. Kumthekar – Northwestern University
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-11 - Focused ultrasound-mediated delivery of anti-programmed cell death-ligand 1 antibody to the brain of a porcine model
Location: Exhibit Hall A/B
Author: Siaka Fadera – Washington University in St Louis
Author: Chinwendu Chukwu – Washington University in St Louis
Author: Andrew H. Stark – Washington University in St Louis
Author: Yimei Yue – Washington University in St Louis
Poster Presenter: Jinyun Yuan – Washington University in St Louis
Author: Chih-Yen Chien – Washington University in St Louis
Author: Lu Xu – Washington University in St Louis
Author: Mohammad Albuhssin – Washington University in St Louis
Author: Hong Chen – Washington University in St Louis
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-14 - Exploring the role of Wnt pathway inhibition on glioma stem cells progression and brain endothelial integrity
Location: Exhibit Hall A/B
Poster Presenter: Kayen Tang – Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH
Author: Jeonghan Kang – National Institutes of Health
Author: Christina Conrad – National Institutes of Health
Author: Sanghee Lim – National Institutes of Health
Author: Minhye Kwak – National Institutes of Health
Author: Melissa Cesaire – National Institutes of Health
Author: Sadhana Jackson – Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH
Drug delivery
Friday, Nov 17th
7:30 PM – 9:30 PM PT
DDEL-15 - Exploring the use of machine learning to predict blood brain barrier permeability of drug molecules
Location: Exhibit Hall A/B
Poster Presenter: Megan Amber Lim – Carle Illinois College of Medicine - University of Illinois at Urbana-Champaign (UIUC)
Author: Wael Hassaneen Mostafa – Carle Neuroscience Institute
Drug delivery
Sunday, Nov 19th
10:35 AM – 10:45 AM PT
DDEL-07 - Barrier to progress: Diffuse Intrinsic Pontine Glioma (DIPG) induces a tightened blood-brain barrier phenotype.
Location: Room 121-122
Oral Abstract Presenter: Caitlin Ung – Children's Cancer Institute Australia
Author: Dannielle Upton – Children's Cancer Institute
Author: Pooja Venkat – Children’s Cancer Institute
Author: Ruby Pandher – Children's Cancer Institute
Author: Chelsea Mayoh – Children's Cancer Institute
Author: Maria Tsoli – Children's Cancer Institute
Author: David S. Ziegler – Kids Cancer Centre, Sydney Children’s Hospital
Drug delivery