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  • Friday, Nov 17th
    10:55 AM – 11:05 AM PT
    EXTH-67 - LP-184, an MGMT-agnostic small molecule, has potent synergy with Spironolactone to effectively inhibit orthotopic GBM xenograft tumors
    Location: Room 109-110
    Author: Bachchu Lal – The Kennedy Krieger Institute
    Author: Aditya Kulkarni – Lantern Pharma
    Author: Joseph McDermott – Lantern Pharma
    Author: Hernando M. Lopez-Bertoni – The Kennedy Krieger Institute
    Author: Kishor Bhatia – Lantern Pharma
    Author: Panna Sharma – Lantern Pharma
    Oral Abstract Presenter: John Laterra – Johns Hopkins School of Medicine
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    11:05 AM – 11:15 AM PT
    EXTH-62 - Combinational treatment of G-quadruplex stabilizer CX-5461 and ionizing radiation potentiates selective lethality in preclinical ATRX-deficient glioma models
    Location: Room 109-110
    Oral Abstract Presenter: Sharvari Dharmaiah – University of Texas MD Anderson Cancer Center
    Author: Prit Benny Malgulwar – University of Texas MD Anderson Cancer Center
    Author: William E Johnson – University of Texas MD Anderson Cancer Center
    Author: Brandon A. A. Chen – University of Texas MD Anderson Cancer Center
    Author: Ahsan S. S. Farooqi – University of Texas MD Anderson Cancer Center
    Author: Jason T. Huse – University of Texas MD Anderson Cancer Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    11:15 AM – 11:25 AM PT
    EXTH-49 - A Novel Multivalent Drug Conjugate for High-grade Glioma Treatment
    Location: Room 109-110
    Oral Abstract Presenter: Roy E. Strowd – Wake Forest University School of Medicine
    Author: Waldemar Debinski – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Author: Kaitlin N Fink – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Author: Denise Herpai – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Author: John H. Rossmeisl – Virginia-Maryland College of Veterinary Medicine
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    11:45 AM – 11:50 AM PT
    EXTH-18 - Development of a Transgenic Mouse Model Enabling Comparative Analysis of chimeric antigen receptor (CAR)-Expressing Immune Cell Populations for Cancer Immunotherapy
    Location: Room 109-110
    Author: Ryusuke Hatae – Department of Neurological Surgery, University of California San Francisco
    Oral Abstract Presenter: Payal Watchmaker – University of California, San Francisco
    Author: Akane Yamamichi – Department of Neurological Surgery, UCSF
    Author: Keith Kyewalabye – University of California, San Francisco
    Author: Kaori Okada – University of California, San Francisco
    Author: Su Phyu – Department of Neurological Surgery, University of California San Francisco
    Author: Yitzhar Goretsky – University of California, San Francisco
    Author: Tiffany Chen – Department of Microbiology and Immunology, Dartmouth College
    Author: Pavlina Chuntova – Department of Neurological Surgery, University of California San Francisco
    Author: Masaki Terabe – National Cancer Institute, NIH
    Author: Hideho Okada – University of California, San Francisco
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    12:00 PM – 12:05 PM PT
    EXTH-45 - Development of combination therapies of KRASG12C inhibitor adagrasib in preclinical models of brain metastasis
    Location: Room 109-110
    Oral Abstract Presenter: Consuelo Torrini – Massachusetts General Hospital
    Author: Christian Migliarese – Massachusetts General Hospital
    Author: Elizabeth J. Summers – Massachusetts General Hospital
    Author: Fatma Turna Demir – Massachusetts General Hospital
    Author: Nazanin Ijad – Massachusetts General Hospital
    Author: Naema Nayyar – Massachusetts General Hospital
    Author: Erika Yamazawa – Massachusetts General Hospital
    Author: Magali De Sauvage – Massachusetts General Hospital
    Author: Priscilla K. Brastianos – Massachusetts General Hospital/Harvard Medical School
    Author: Hiroaki Wakimoto – Harvard Medical School
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    3:00 PM – 3:10 PM PT
    EXTH-36 - Combining ONC201 and paxalisib for the treatment of diffuse midline glioma (DMG); the preclinical results underpinning the international Phase II clinical trial (NCT05009992).
    Location: Exhibit Hall C
    Plenary Abstract Presenter: Evangeline R. Jackson – University of Newcastle
    Author: Ryan J. Duchatel – University of Newcastle
    Author: Dilana Staudt – University of Newcastle
    Author: Mika L. Persson – University of Newcastle
    Author: Abdul Mannan – University of Newcastle
    Author: Sridevi Yadavilli – Children's National Hospital
    Author: Sarah G. Parackal – Hudson Institute of Medical Research
    Author: Shaye Game – Hudson Institute of Medical Research
    Author: Wai Chin Chong – Hudson Institute of Medical Research
    Author: W. Samantha Jayasekara – Hudson Institute of Medical Research
    Author: Marion Le Grand – Aix-Marseille Universite, Inserm, CNRS, Institut Paoli Calmettes
    Author: Padraic S. Kearney – University of Newcastle
    Author: Alicia M. Douglas – University of Newcastle
    Author: Izac J. Findlay – University of Newcastle
    Author: Zacary Germon – University of Newcastle
    Author: Holly McEwen – University of Newcastle
    Author: Tyrone Beitaki – University of Newcastle
    Author: Adjanie Patabendige – Edge Hill University
    Author: David Skerrett-byrne – University of Newcastle
    Author: Brett Nixon – University of Newcastle
    Author: Nathan Smith – University of Newcastle
    Author: Bryan W. Day – Sid Faithfull Brain Cancer Laboratory, QIMR Berghofer
    Author: Neevika Manoharan – Sydney Children's Hospital
    Author: Sumanth Nagabushan – Sydney Children's Hospital
    Author: Jordan R. Hansford – Children's Cancer Centre, Royal Children’s Hospital Melbourne
    Author: Dinisher Govender – The Children's Hospital at Westmead
    Author: Geoffrey McCowage – Sydney Children’s Hospitals Network
    Author: Ron Firestein – Hudson Institute of Medical Research
    Author: Meegan Howlett – University of Western Australia
    Author: Raelene Endersby – University of Western Australia
    Author: Nicholas G. Gottardo – Perth Children's Hospital
    Author: Frank Alvaro – University of Newcastle
    Author: Sebastian M. Waszak – École Polytechnique Fédérale de Lausanne (EPFL)
    Author: Martin R. Larsen – University of South Denmark
    Author: Yolanda Colino Sanguino – Children's Cancer Institute
    Author: Fatima Valdes-Mora – Children's Cancer Institute
    Author: Andria Rakotomalala – Centre Oscar Lambret
    Author: Samuel Meignan – Centre Oscar Lambret
    Author: Eddy Pasquier – Aix-Marseille Universite, Inserm, CNRS, Institut Paoli Calmettes
    Author: Nicolas Andre – Aix-Marselle Universite, Inserm, CNRS, Institut Paoli Calmettes
    Author: Esther Hulleman – Princess Máxima Center for Pediatric Oncology
    Author: David D. Eisenstat – The Royal Children’s Hospital Melbourne
    Author: Nicholas A. Vitanza – Seattle Children’s
    Author: Javad Nazarian – University Children’s Hospital Zurich
    Author: Carl J. Koschmann – University of Michigan
    Author: Sabine Mueller – University of California, San Francisco
    Author: Jason E. Cain – Hudson Institute of Medical Research
    Author: Matthew D. Dun – University of Newcastle
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    3:45 PM – 3:55 PM PT
    EXTH-31 - Exploiting the genetic dependency on PI3K/mTOR signaling for the treatment of H3-altered diffuse midline glioma
    Location: Room 121-122
    Oral Abstract Presenter: Ryan J. Duchatel – University of Newcastle
    Author: Evangeline R. Jackson – University of Newcastle
    Author: Sarah G. Parackal – Hudson Institute of Medical Research
    Author: Claire Sun – Hudson Institute of Medical Research
    Author: Paul Daniel – Hudson Institute of Medical Research
    Author: Abdul Mannan – University of Newcastle
    Author: Izac J. Findlay – University of Newcastle
    Author: Dilana Staudt – University of Newcastle
    Author: Zacary Germon – University of Newcastle
    Author: Sandra Laternser – University Children’s Hospital Zürich
    Author: Dylan Kiltschewskij – University of Newcastle
    Author: Padraic S. Kearney – University of Newcastle
    Author: M. Fairuz B. Jamaluddin – University of Newcastle
    Author: Alicia M. Douglas – University of Newcastle
    Author: Tyrone Beitaki – University of Newcastle
    Author: Mika Perrson – University of Newcastle
    Author: Bryce Thomas – University of Newcastle
    Author: Elizabeth E. Manning – University of Newcastle
    Author: Heather C. Murray – University of Newcastle
    Author: Nikki M. Verrills – University of Newcastle
    Author: Ricardo Vilain – University of Newcastle
    Author: David Skerrett-byrne – University of Newcastle
    Author: Brett Nixon – University of Newcastle
    Author: Susan Hua – University of Newcastle
    Author: Charles DeBock – Children's Cancer Institute
    Author: Fatima Valdes-Mora – Children's Cancer Institute
    Author: Maria Tsoli – Children's Cancer Institute
    Author: David S. Ziegler – Kids Cancer Centre, Sydney Children’s Hospital
    Author: Murray Cairns – University of Newcastle
    Author: Eric Raabe – Johns Hopkins University
    Author: Nicholas A. Vitanza – Seattle Children’s
    Author: Timothy N. Phoenix – University of Cincinnati
    Author: Carl J. Koschmann – University of Michigan
    Author: Frank Alvaro – University of Newcastle
    Author: Christopher V. Dayas – University of Newcastle
    Author: Christopher Tinkle – St. Jude Children’s Research Hospital
    Author: David D. Eisenstat – The Royal Children’s Hospital Melbourne
    Author: Ron Firestein – Hudson Institute of Medical Research
    Author: Sabine Mueller – University of California, San Francisco
    Author: Javad Nazarian – University Children’s Hospital Zurich
    Author: Jason E. Cain – Hudson Institute of Medical Research
    Author: Matthew D. Dun – University of Newcastle
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    4:05 PM – 4:15 PM PT
    EXTH-75 - A macrophage-based drug delivery platform for glioma treatment
    Location: Room 118-120
    Oral Abstract Presenter: Miaomiao Sun – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Switzerland
    Author: Maciej Bialasek – Department of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, Poland
    Author: Tomasz Rygiel – Laboratory of Immunology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland
    Author: Michael Weller – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Magdalena Krol – Department of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, Poland
    Author: Tobias Weiss – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    4:15 PM – 4:25 PM PT
    EXTH-29 - Interneurons that BiTE, a cellular therapy for High Grade Glioma
    Location: Room 118-120
    Author: Stephanie Brosius – Children's Hospital Philadelphia
    Author: William Manley – Children's Hospital Philadelphia
    Author: Stewart Anderson – Children's Hospital Philadephia
    Oral Abstract Presenter: Thomas De Raedt – Children's Hospital Philadelphia
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    4:55 PM – 5:00 PM PT
    EXTH-80 - A systemic comparison of CAR T cells, CAR NK cells and CAR macrophages for glioma treatment
    Location: Room 118-120
    Author: Thomas Look – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Serena Fazio – Department of Medical Oncology and Hematology, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Niklas Binder – Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany
    Author: Charles L. Sentman – Center for Synthetic Immunity and Department of Microbiology & Immunology, Geisel School of Medicine, Lebanon, N.H., USA
    Author: Patrick Roth – Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Cesar Nombela Arrieta – Department of Medical Oncology and Hematology, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Roman Sankowski – Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany
    Author: Steve Pascolo – Department of Dermatology, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Michael Weller – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Oral Abstract Presenter: Tobias Weiss – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:50 PM – 7:54 PM PT
    EXTH-04 - Cytostatic hypothermia against glioblastoma and the development of a neural implant for rodents and swine
    Location: Exhibit Hall A/B
    Rapid and Poster Presenter: Syed Faaiz Enam – UT Southwestern Medical Center
    Author: Reed Chen – Duke University
    Author: Mahabad Barwari – UT Dallas
    Author: Aksharkumar Dobariya – UT Southwestern Medical Center
    Author: Ankur Patel – UT Southwestern Medical Center
    Author: Toral R. Patel – UT Southwestern Medical Center
    Author: Ravi Bellamkonda – Emory University
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:54 PM – 7:58 PM PT
    EXTH-33 - RAGE inhibitor (TTP488) as an alternative to dexamethasone for managing cerebral edema following brain tumor surgery
    Location: Exhibit Hall A/B
    Rapid and Poster Presenter: Mojtaba Dayyani – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Aleksandr Filippov – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Ian Zhang – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Joseph Georges – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Zaan Saeed – City of Hope National Medical Center
    Author: Jillyn Turunen – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Larry Zhang – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Rachel Maus – Department of Medical Oncology, City of Hope Beckman Research Institute
    Author: Jana L. Portnow – Department of Medical Oncology, City of Hope Beckman Research Institute
    Author: Behnam Badie – Division of Neurosurgery, City of Hope Beckman Research Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:58 PM – 8:02 PM PT
    EXTH-74 - Tumor pharmacokinetics and pharmacodynamics in patient-derived xenograft models of glioblastoma treated with the PRMT5 inhibitor SKL27969
    Location: Exhibit Hall A/B
    Rapid and Poster Presenter: An-Chi Tien – Ivy Brain Tumor Center
    Author: Tigran Margaryan – Ivy Brain Tumor Center
    Author: Jennifer Molloy – Ivy Brain Tumor Center
    Author: James McNamara – Ivy Brain Tumor Center
    Author: William L. Knight – Ivy Brain Tumor Center/University of Arizona College of Medicine
    Author: Raymond Hon – Ivy Brain Tumor Center
    Author: Zorana Opachich – Ivy Brain Tumor Center
    Author: Ernesto Luna Melendez – Ivy Brain Tumor Center
    Author: Mackenna Elliott – Ivy Brain Tumor Center
    Author: Connor White – Ivy Brain Tumor Center
    Author: Nader Sanai – Barrow Neurological Institute
    Author: Artak Tovmasyan – Barrow Neurological Institute
    Author: Shwetal Mehta – Ivy Brain Tumor Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    8:02 PM – 8:06 PM PT
    EXTH-85 - EphA3 CART: Dual Targeting of Glioblastoma and Tumor Microenvironment
    Location: Exhibit Hall A/B
    Rapid and Poster Presenter: Michael W. Ruff – Mayo Clinic
    Author: Ekene Ogbodo – Mayo Clinic
    Author: Elizabeth Siegler – Mayo Clinic
    Author: Leo Sakemura – Mayo Clinic
    Author: Jann N. Sarkaria – Mayo Clinic
    Author: Saad Kenderian – Mayo Clinic
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-01 - Stem cell therapy for leptomeningeal disease
    Location: Exhibit Hall A/B
    Poster Presenter: Yohei Kitamura – Keio University School of Medicine
    Author: Nobuhiko Kanaya – Okayama University
    Author: Susana Moleirinho – Universidade de Lisboa
    Author: Ryota Tamura – keio University
    Author: Ryo Ueda – Keio University
    Author: Hikaru Sasaki – Tokyo Dental College Ichikawa General Hospital, Department of Neurosurgery
    Author: Masahiro Toda – Keio University School of Medicine
    Author: Khalid Shah – Harvard Medical School
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-02 - A TERT-specific TCR-like antibody CAR T cell approach facilitates killing of glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Eric Zhu – Washington University School of Medicine
    Author: Susan Gladney – Washington University School of Medicine
    Author: Julie Ritchey – Washington University School of Medicine
    Author: Alexandra J. Livingstone – Washington University School of Medicine
    Author: Julie O'Neal – Washington University School of Medicine
    Author: Tanner M. Johanns – Washington University School of Medicine
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-04 - Cytostatic hypothermia against glioblastoma and the development of a neural implant for rodents and swine
    Location: Exhibit Hall A/B
    Poster Presenter: Syed Faaiz Enam – UT Southwestern Medical Center
    Author: Reed Chen – Duke University
    Author: Mahabad Barwari – UT Dallas
    Author: Aksharkumar Dobariya – UT Southwestern Medical Center
    Author: Ankur Patel – UT Southwestern Medical Center
    Author: Toral R. Patel – UT Southwestern Medical Center
    Author: Ravi Bellamkonda – Emory University
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-05 - Anti-tumor immune response of Oncomagnetic monotherapy in glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Arvind Pandey – Houston Methodist Research Institute
    Author: Shashank Hambarde – Houston Methodist Research Institute
    Author: David S. S. Baskin – Houston Methodist Hospital
    Author: Santosh A. A. Helekar – Houston Methodist Reserach Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-06 - Glioblastoma patient specific transcriptome remodeling  in response to MDM2 antagonist treatment of wild-type p53  cancer stem cells is associated with sensitivity and strategies for combination therapy
    Location: Exhibit Hall A/B
    Author: Yuling Meng – Henry Ford Health
    Author: Nouman Mughal – Aga Khan University
    Author: Indrani Datta – Henry Ford Health
    Author: Oluwademilade Nuga – Wayne State University
    Author: Susan Irtenkauf – Henry Ford Health
    Author: Laura A. Hasselbach – Henry Ford Health
    Author: Kristyn Quenneville – Henry Ford Health
    Author: Stephen L. Brown – Henry Ford Health
    Poster Presenter: Ana C. deCarvalho – Henry Ford Health
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-07 - Neoadjuvant PD1 blockade alters the tumor microenvironment post-surgery in a preclinical model of recurrent glioblastoma
    Location: Exhibit Hall A/B
    Author: Lan B. Hoang-Minh – University of Florida
    Author: Duane A. Mitchell – University of Florida
    Author: Kelena Klippel – University of Florida
    Poster Presenter: Changlin Yang – University of Florida
    Author: Vrunda Trivedi – University of Florida
    Author: Bently Doonan – University of Florida
    Author: Christina A. von Roemeling – University of Florida
    Author: Oleg Yegorov – University of Florida
    Author: Akshayaa Sriharan – Univ
    Author: Connor Francis – University of Florida
    Author: David Shin – University of Florida
    Author: Aida Karachi – University of Florida
    Author: Matthew Sarkisian – University of Florida
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-08 - Immunotherapeutic targeting of Fibroblast Activation Protein (FAP) in treatment refractory Glioblastoma using novel CAR-T cell therapy
    Location: Exhibit Hall A/B
    Poster Presenter: Nazanin Tatari – University Hospital Basel
    Author: Hayget Mohamed Seid Hedad – University Hospital Basel
    Author: Andreas Zingg – University Hospital Basel
    Author: Ewelina.M Bartoszek – University of Basel
    Author: Viviane.J Tschan – University Hospital Basel
    Author: Timo Schenker – University Hospital Basel
    Author: Marie-Françoise Ritz – University of Basel
    Author: Petar Miletic – McMaster University
    Author: Chitra Venugopal – McMaster University
    Author: Manina.M Etter – University Hospital Basel
    Author: Sheila.K K. Singh – McMaster University
    Author: Heinz Läubli – University Hospital Basel
    Author: Gregor Hutter – University Hospital Basel
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-09 - GM-CSF and IL-7 Fusion Cytokine Engineered Tumor Vaccine Generates Long-termTh-17 Memory Cells and Increases Overall Survival in Aged Syngeneic Mouse Models of Glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Jack M. Shireman – UW-Madison
    Author: Nikita Gonugunta – UW-Madison
    Author: Akshita Pattnaik – UW-Madison
    Author: Lei Zhao – UW_Madison
    Author: Xiaohu Wang – UW-Madison
    Author: Jacques Galipeau – UW-Madison
    Author: Mahua Dey – UW-Madison
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-10 - QUAD-DM1: A Highly Potent Drug Conjugate for Breast Cancer and Breast Cancer Brain Metastasis Treatment
    Location: Exhibit Hall A/B
    Author: Waldemar Debinski – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Author: Kaitlin N Fink – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Author: John H. Rossmeisl – Virginia-Maryland College of Veterinary Medicine
    Author: Ryan T Mott – Wake Forest University School of Medicine
    Poster Presenter: Denise Herpai – Atrium Health Wake Forest Baptist Comprehensive Cancer Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-11 - Adoptive cellular therapy overcomes glioma immune escape by disrupting MDSC proliferation and recruitment
    Location: Exhibit Hall A/B
    Poster Presenter: John Figg – University of Florida
    Author: Connor Francis – University of Florida
    Author: Dan Jin – University of Florida
    Author: Bayli DiVita Dean – University of Florida
    Author: Laura Falceto Font – UF
    Author: Alexandra Reid – University of Florida
    Author: Brianna McDonald – University of Florida
    Author: David Hilferty – UF
    Author: Kaytora Long-James – University of Florida
    Author: Catherine Flores – University of Florida
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-12 - Cytochrome c oxidase subunit 4 isoform 1 mediates oncolytic herpes simplex virus-1 efficacy in high-grade glioma
    Location: Exhibit Hall A/B
    Poster Presenter: Sam E. Gary – University of Alabama at Birmingham
    Author: Vincent M. Laufer – University of Michigan
    Author: Kaysaw Tuy – University of Alabama at Birmingham
    Author: Kyung-Don Kang – University of Alabama at Birmingham
    Author: Claudia R. Oliva – University of Alabama at Birmingham
    Author: Corinne E. Griguer – The University of Iowa
    Author: Anita B. Hjelmeland – University of Alabama at Birmingham
    Author: Gregory K. Friedman – University of Alabama at Birmingham
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-14 - mRNA-loaded exosomes for targeted glioblastoma immunotherapy
    Location: Exhibit Hall A/B
    Poster Presenter: Kristin Huntoon – UT-MD Anderson Cancer Center
    Author: Shiyan Dong – MD Anderson Cancer Center
    Author: Abin Antony – MD Anderson Cancer Center
    Author: Yifan Wang – MD Anderson Cancer Center
    Author: Betty Kim – MD Anderson Cancer Center
    Author: Wen Jiang – MD Anderson Cancer Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-15 - A novel immune-based treatment strategy for combatting protein tumor heterogeneity
    Location: Exhibit Hall A/B
    Poster Presenter: Daniel Wilkinson – Duke University
    Author: Ethan S. Srinivasan – Johns Hopkins Department of Neurosurgery
    Author: Emily C. Lerner – Duke University School of Medicine
    Author: Peter E. Fecci – Duke University Department of Neurosurgery
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-20 - A mouse model reveals vulnerability of IDH1-mutated glioma to Ferroptosis
    Location: Exhibit Hall A/B
    Poster Presenter: Angeliki Mela – Columbia University Medical Center
    Author: Athanassios Dovas – Columbia University Medical Center
    Author: Aayushi Mahajan – Columbia University Medical Center
    Author: Nelson Humala – Columbia University Medical Center
    Author: Trang Nguyen – Columbia University Medical Center
    Author: Smriti Kanangat – Columbia University Medical Center
    Author: Pavan S. Upadhyayula – Columbia University Medical Center
    Author: Lisa Sprinzen – University of California San Francisco
    Author: Michael G. Argenziano – Columbia University Medical Center
    Author: Dennis Huang – ASRC, City University of New York
    Author: Jia Guo – Columbia University
    Author: Patrizia Casaccia – ASRC, City University of New York
    Author: Markus D. Siegelin – Columbia University Medical Center
    Author: Brent Stockwell – Columbia University
    Author: Jeffrey N. Bruce – Columbia University Medical Center
    Author: Peter D. Canoll – Columbia University Irving Medical Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-21 - FKBP38 regulates self-renewal and survival of GBM neurospheres  
    Location: Exhibit Hall A/B
    Author: Aimee Dowling – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Stuart Walbridge – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Celine Ertekin – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Jean-Paul Bryant – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Eric Kohut – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Ashis Chowdhury – Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Author: Desmond A. Brown – Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH
    Author: John D. Heiss – National Institute of Neurological Disorders and Stroke
    Poster Presenter: Yeshavanth Kumar K. Banasavadi-Siddegowda – Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-23 - Effect of evogliptin and temozolomide combination therapy for the treatment of glioblastoma, in vitro and in vivo
    Location: Exhibit Hall A/B
    Poster Presenter: Seung Ho Yang – Department of Neurosurgery, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Author: Keun Soo lee – Department of Neurosurgery, Inje University Busan Paik Hospital
    Author: Jung Eun Lee – Department of Neurosurgery, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-24 - Fc-enhanced anti-CTLA-4 immune checkpoint blockade and its combination with anti-PD-1 with concomitant doxorubicin and ultrasound-mediated BBB opening: A novel immunotherapy for glioblastoma.
    Location: Exhibit Hall A/B
    Poster Presenter: Kwang-Soo Kim – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Karl Habashy – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Andrew Gould – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Hinda Najem – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Junfei Zhao – Columbia University
    Author: Christina Amidei – Northwestern University
    Author: Ruth Saganty – Northwestern University
    Author: Victor A. Arrieta – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Crismita Dmello – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Li Chen – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Daniel Zhang – Northwestern University
    Author: Brandyn Castro – Northwestern University
    Author: Leah Billingham – Northwestern University
    Author: Daniel Levey – Agenus
    Author: Benjamin Morin – Agenus
    Author: Miguel Muzzio – IIT Research Institute
    Author: Michael Canney – Carthera
    Author: Katy McCortney – Northwestern University
    Author: Craig Horbinski – Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
    Author: Peng Zhang – Northwestern University
    Author: Jason Miska – Northwestern University
    Author: Raul Rabadan – Columbia University
    Author: Amy B. Heimberger – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Roger Stupp – Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
    Author: Dhan Chand – Agenus
    Author: Catalina L. Lee-Chang – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University
    Author: Adam M. Sonabend – Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-25 - In vivo two-photon tumor imaging in an orthotopic medulloblastoma mouse model
    Location: Exhibit Hall A/B
    Poster Presenter: Nico Teske – Department of Neurosurgery, LMU University Hospital Munich
    Author: Nayad N. Kutlu – Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Julika J. Herold – Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Laura Dengler – Department of Neurosurgery, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Constantin Eberle – Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Elene Nikolaishvili – Department of Neurology, University Hospital of the Ludwig-Maximilians-University Munich, Munich, Germany
    Author: Philipp Karschnia – Dept. of Neurosurgery, Ludwig Maximilians University (LMU) Munich,
    Author: Jens Blobner – Department of Neurosurgery, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Katharina Müller – Dept. of Neurology, Ludwig Maximilians University (LMU),
    Author: Sigrid Langer – Department of Neurology, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Vincenz Buschinger – nstitute for Medical Microbiology, Immunology and Hygiene, Technische Universitaet Muenchen (TUM)
    Author: Linda Warmuth – nstitute for Medical Microbiology, Immunology and Hygiene, Technische Universitaet Muenchen (TUM)
    Author: Dirk H. Busch – nstitute for Medical Microbiology, Immunology and Hygiene, Technische Universitaet Muenchen (TUM)
    Author: Veit Buchholz – Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany
    Author: Niklas Thon – Department of Neurosurgery, University Hospital, LMU Munich
    Author: Joerg-Christian Tonn – Department of Neurosurgery, University Hospital, LMU Munich
    Author: Tobias Feuchtinger – Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Louisa von Baumgarten – Dept. of Neurosurgery, Ludwig Maximilians University (LMU) Munich,
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-26 - 3D live microscopy and single cell transcriptomic to decipher molecular actors involved in glioblastoma cell invasion in human cerebral organoids
    Location: Exhibit Hall A/B
    Poster Presenter: Maite Verreault – Paris Brain Institute
    Author: David Akbar – Paris Brain Institute
    Author: Emeline Cherchame – Paris Brain Institute
    Author: Benjamin Galet – Paris Brain Institute
    Author: Emie Quissac – Paris Brain Institute
    Author: Philippe Ravassard – Paris Brain Institute
    Author: Ahmed Idbaih – Sorbonne Université, AP-HP, ICM, Hôpital Universitaire La Pitié-Salpêtrière
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-27 - Assesing the effect of Electric Field Therapy on patient derived Glioma stem cell lines and Glioma infiltrating cerebral organoids.
    Location: Exhibit Hall A/B
    Author: Ashwin Narayanan – QV bioelectronics Ltd
    Author: Jinwei Zhao – QV bioelectronics
    Poster Presenter: Tomisin Olukoga – QV Bioelectronics Ltd
    Author: Christopher Bullock – QV Bioelectronics Ltd
    Author: Richard Fu – QV Bioelectronics Ltd
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-32 - Synergistic efficacy of Y box binding protein 1 (YBX1) inhibition combined with chemotherapy for the treatment of MYC-amplified medulloblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Stephen Carney – Seattle Children's Research Institute
    Author: Christian Bonatto – Allen Brain Institute
    Author: Guadalupe Guadarrama – University of Washington
    Author: Dhanir Tailor – Oregon Health & Science University
    Author: Sanjay Malhotra – Oregon Health & Science University
    Author: Myron Evans, II – Seattle Childrens Research Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-33 - RAGE inhibitor (TTP488) as an alternative to dexamethasone for managing cerebral edema following brain tumor surgery
    Location: Exhibit Hall A/B
    Poster Presenter: Mojtaba Dayyani – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Aleksandr Filippov – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Ian Zhang – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Joseph Georges – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Zaan Saeed – City of Hope National Medical Center
    Author: Jillyn Turunen – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Larry Zhang – Division of Neurosurgery, City of Hope Beckman Research Institute
    Author: Rachel Maus – Department of Medical Oncology, City of Hope Beckman Research Institute
    Author: Jana L. Portnow – Department of Medical Oncology, City of Hope Beckman Research Institute
    Author: Behnam Badie – Division of Neurosurgery, City of Hope Beckman Research Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-35 - Unraveling the mechanistic underpinnings of mRNA vaccine mediated innate immune activation and lymphocyte trafficking for high-grade gliomas
    Location: Exhibit Hall A/B
    Poster Presenter: Anna DeVries – University of Florida
    Author: Hector Mendez-Gomez – University of Florida
    Author: Jonathan Chardon-Robles – University of Florida
    Author: Nagheme Thomas – University of Florida
    Author: James McGuiness – University of Florida
    Author: Sheila Carrera-Justiz – University of Florida
    Author: Paul Castillo – University of Florida
    Author: Frances Weidert – University of Florida
    Author: Duane A. Mitchell – University of Florida
    Author: Elias Sayour – University of Florida
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-37 - Functional genomics identifies therapeutic vulnerabilities of glioma subtypes and YAP/TAZ-enriched tumors
    Location: Exhibit Hall A/B
    Poster Presenter: Wan-Hsin Lin – Mayo Clinic Florida
    Author: Farhad Kosari – Mayo Clinic Rochester
    Author: James Smadbeck – Mayo Clinic Rochester
    Author: Michael Barrett – Mayo Clinic Arizona
    Author: Ryan W. Feathers – Mayo Clinic Florida
    Author: Alan Penheiter – Mayo Clinic Rochester
    Author: Jamie Lynch – Mayo Clinic Florida
    Author: Sotiris Sotiriou – Mayo Clinic Rochester
    Author: Dorsay Sadeghian – Mayo Clinic Rochester
    Author: Vijaya Kadam Maruthi – Mayo Clinic Rochester
    Author: Sarah Johnson – Mayo Clinic Rochester
    Author: Giannoula Karagouga – Mayo Clinic Rochester
    Author: Faye R. Harris – Mayo Clinic Rochester
    Author: Taylor Berry – Mayo Clinic Florida
    Author: Alexa McCune – Mayo Clinic Rochester
    Author: Stephen Murphy – Mayo Clinic Rochester
    Author: Lindsey Kinsella – Mayo Clinic Florida
    Author: Diogo Moniz-Garcia – Mayo Clinic Florida
    Author: Shannon Fortin Ensign – Mayo Clinic Arizona
    Author: Lin Yang – Mayo Clinic Rochester
    Author: Angela Emanuel – Mayo Clinic Rochester
    Author: Rebecca Salvatori – Mayo Clinic Rochester
    Author: Janet Schaefer Klein – Mayo Clinic Rochester
    Author: Cristiane M. Ida – Mayo Clinic Rochester MN
    Author: Mark E. Jentoft – Mayo Clinic Florida
    Author: Marcela Salomao – Mayo Clinic Arizona
    Author: Wendy J. Sherman – Mayo Clinic Florida
    Author: Alyx B. Porter – Mayo Clinic Arizona
    Author: Steven S. Rosenfeld – Mayo Clinic Florida
    Author: Sani H. Kizilbash – Mayo Clinic (Rochester)
    Author: Kurt A. Jaeckle – Mayo Clinic Florida
    Author: Maciej M. Mrugala – Mayo Clinic Arizona
    Author: Aaron S. Mansfield – Mayo Clinic Rochester
    Author: Mitesh Borad – Mayo Clinic Arizona
    Author: Bernard R. Bendok – Mayo Clinic Arizona, Department of Neurosurgery
    Author: Terry C. Burns – Mayo Clinic Rochester
    Author: Alfredo Quiñones-Hinojosa – Mayo Clinic Florida
    Author: John Cheville – Mayo Clinic Rochester
    Author: George Vasmatzis – Mayo Clinic Rochester
    Author: Panos Z. Anastasiadis – Mayo Clinic Florida
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-38 - Velcrin molecular glues induce cell death in glioblastomas with high PDE3A and SLFN12 expression.
    Location: Exhibit Hall A/B
    Poster Presenter: Elisa Aquilanti – Dana Farber Cancer Institute
    Author: Silvia Goldoni – Bayer AG
    Author: Andrew Baker – Johns Hopkins University
    Author: Kristina Kotynkova – Broad Institute
    Author: Sawyer Andersen – Broad institute
    Author: Galen Gao – UT Southwestern
    Author: Andrew Cherniack – Broad Institute
    Author: Martin Lange – Nuvisan
    Author: Charlotte Kopitz – Nuvisan
    Author: Philip Lienau – Bayer AG
    Author: Timothy Lewis – Broad Institute
    Author: Marine Garrido – Bayer AG
    Author: Stefan Gradl – Bayer AG
    Author: Henrik Seidel – Bayer AG
    Author: Keith L. Ligon – Brigham and Women's Hospital
    Author: Patrick Y. Wen – Dana-Farber Cancer Institute
    Author: Matthew Meyerson – Dana Farber Cancer institute
    Author: Heidi Greulich – Broad Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-39 - D2C7-CAR: A novel, dual-specific chimeric antigen receptor T cell with high specificity for EGFR and EGFRvIII improves survival in EGFR/EGFRvIII glioblastoma and EGFR over-expressing medulloblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Zach Wilson – Duke University
    Author: Daniel Wilkinson – Duke University
    Author: Katherine J. Ryan – Duke University
    Author: Vidya Chandramohan – Duke University
    Author: Darell D. Bigner – Duke University
    Author: Peter E. Fecci – Duke University Department of Neurosurgery
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-40 - Photodynamic oncolytic virus therapy for central nervous system malignancies
    Location: Exhibit Hall A/B
    Poster Presenter: Kazuhide Shimizu – Tokyo Medical and Dental University
    Author: Andranik Kahramanian – The Royal Melbourne Hospital
    Author: Taketoshi Maehara – Tokyo Medical and Dental University
    Author: Hiroaki Wakimoto – Harvard Medical School
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-41 - Combination treatment of calcium channel antagonist mibefradil enhances the effect of hydroxyurea at therapeutic ranges in high-grade meningioma in vitro.
    Location: Exhibit Hall A/B
    Poster Presenter: Erik White – Loyola University Health and Science
    Author: Michael Prabhu – University of Illinois Urbana-Champaign
    Author: Jigisha P. Thakkar – Loyola University Stritch School of Medicine
    Author: Kevin Barton – Loyola University Stritch School of Medicine
    Author: Vikram C. Prabhu – Loyola University Stritch School of Medicine
    Author: Erika Piedras-Renteria – Loyola University Health and Science
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-43 - Targeting the DNA damage response through combination MDM2 and AKT inhibitor therapy improves temozolomide effectiveness in chemo-resistant glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Jenna K. Koenig – Indiana University School of Medicine
    Author: Barbara J. Bailey – Indiana University School of Medicine
    Author: Anthony Alfonso – Indiana University School of Medicine
    Author: M. Reza Saadatzadeh – Indiana University School of Medicine
    Author: Khadijeh Bijangi-Vishehsaraei – Indiana University School of Medicine
    Author: Pankita H. Pandya – Indiana University School of Medicine
    Author: Nur P. Damayanti – Indiana University School of Medicine
    Author: Erika A. Dobrota – Indiana University School of Medicine
    Author: Courtney Young – Indiana University School of Medicine
    Author: Harlan E. Shannon – Indiana University School of Medicine
    Author: Karen E. Pollok – Indiana University School of Medicine
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-44 - Enhancing Glioblastoma Clearance: Empowering anti-EGFRvIII CAR T Cells with a Paracrine SIRPγ-Derived CD47 Blocker
    Location: Exhibit Hall A/B
    Author: Tomas A. Martins – Universität Basel
    Author: Nazanin Tatari – University Hospital Basel
    Author: Deniz Kaymak – Universität Basel
    Author: Ewelina.M Bartoszek – University of Basel
    Author: Sabrina Hogan – Universität Basel
    Author: Alicia Buck – University of Zurich
    Author: Marie-Françoise Ritz – University of Basel
    Author: Ronja Wieboldt – University of Basel
    Author: Marta McDaid – University of Basel: Universitat Basel
    Author: Alexandra Gerber – University of Basel
    Author: Tala Shekarian – Universität Basel
    Author: Hayget Mohamed Seid Hedad – University Hospital Basel
    Author: Philip Schmassmann – University of Basel
    Author: Tobias Weiss – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Heinz Laeubli – University Hospital Basel
    Poster Presenter: Gregor Hutter – University Hospital Basel
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-47 - Tumour-Targeted pan-RAS Inhibition as a Novel Therapy for Diffuse Intrinsic Pontine Glioma (DIPG)
    Location: Exhibit Hall A/B
    Poster Presenter: Stefanie-Grace Sbergio – The Hospital for Sick Children
    Author: Peter Liang – The Hospital for Sick Children
    Author: Greg Beilhartz – The Hospital for Sick Children
    Author: Palak G. Patel – The Hospital for Sick Children
    Author: Arun Anguraj Vadivel – The Hospital for Sick Children
    Author: Roman Melnyk – The Hospital for Sick Children
    Author: Cynthia Hawkins – The Hospital for Sick Children
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-48 - Protoporphyrin IX levels in patients’ plasma, blood, and brain tumor by a validated LC-MS/MS method
    Location: Exhibit Hall A/B
    Poster Presenter: William L. Knight – Ivy Brain Tumor Center/University of Arizona College of Medicine
    Author: Tigran Margaryan – Ivy Brain Tumor Center
    Author: Nader Sanai – Barrow Neurological Institute
    Author: Artak Tovmasyan – Barrow Neurological Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-50 - Acute and long-term responses to quisinostat treatment in PDX models of glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Keely Orndorff – Barrow Neurological Institute
    Author: James McNamara – Ivy Brain Tumor Center
    Author: Costanza LoCascio – Ivy Brain Tumor Center
    Author: Connor White – Ivy Brain Tumor Center
    Author: Mariya Stavnichuk – Ivy Brain Tumor Center
    Author: Kamal Shaik – Ivy Brain Tumor Center
    Author: Tigran Margaryan – Ivy Brain Tumor Center
    Author: Artak Tovmasyan – Barrow Neurological Institute
    Author: Nader Sanai – Barrow Neurological Institute
    Author: Shwetal Mehta – Ivy Brain Tumor Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-52 - Long-acting recombinant interleukin-7, NT-I7, improves survival following oncolytic Zika virus treatment in the SB28 immunosuppressive and treatment-resistant murine glioma model
    Location: Exhibit Hall A/B
    Poster Presenter: Yuping D. Li – Washington University
    Author: Tong Hu – Washington University in St. Louis
    Author: Ashwani Kesarwani – Washington University
    Author: Amanda De Andrade Costa – Washington University in St. Louis
    Author: Ritvik Illindala – Washington University
    Author: Alexandra Wolfarth – NeoImmuneTech Inc.
    Author: Sara Ferrando-Martinez – NeoImmuneTech Inc.
    Author: Se Hwan Yang – NeoImmuneTech Inc.
    Author: Byung Ha Lee – NeoImmuneTech Inc.
    Author: Michael S. Diamond – Washington University in St. Louis
    Author: Milan G. Chheda – Washington University in St. Louis
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-53 - VEGFR2-specific CAR-T cells show improved tumor infiltration in syngeneic mouse glioma models
    Location: Exhibit Hall A/B
    Poster Presenter: Maximilian Mastall – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Gina Dunkel – Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tuebingen, Tuebingen, Germany
    Author: Manuela Silginer – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Naoki Okada – Laboratory of Vaccine and Immune Regulation (BIKEN), Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
    Author: Tobias Weiss – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Michael Weller – Department of Neurology and Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland
    Author: Bettina Weigelin – Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University of Tuebingen, Tuebingen, Germany
    Author: Patrick Roth – Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-54 - GB13 is a potent treatment for IL13Ra2-expressing GBM and DMG and improves standard-of-care therapy
    Location: Exhibit Hall A/B
    Author: Julian S. Rechberger – Mayo Clinic Rochester
    Author: Liang Zhang – Nanostring
    Author: Harrison Laukhuff – Targepeutics
    Author: maija Woodruff – Targepeutics
    Author: Jann N. Sarkaria – Mayo Clinic
    Author: David J. Daniels – Mayo Clinic Rochester
    Poster Presenter: Randy Schrecengost – Targepeutics
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-55 - All-in-one genetic construct to knockdown miR-21 reduces glioma proliferation in vitro. 
    Location: Exhibit Hall A/B
    Poster Presenter: Lisa Nieland – Massachusetts General Hospital
    Author: Anne Vrijmoet – Massachusetts General Hospital
    Author: Alexandra de Reus – Massachusetts General Hospital
    Author: Benjamin Kleinsteiver – Massachusetts General Hospital
    Author: Marike Broekman – Haaglanden Medical Center
    Author: Xandra Breakefield – Massachusetts General Hospital
    Author: Erik Abels – Leiden University Medical Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-56 - CSF Penetration Comparison of Two Oral Formulations of APL-101 in a Pre-Clinical Non-Human Primate Model
    Location: Exhibit Hall A/B
    Poster Presenter: Natalia Corvalan Cabanas – National Institutes of Health
    Author: Cynthia M. Lester McCully – National Institutes of Health
    Author: Cody J. Peer – National Institutes of Health
    Author: Andrea M. Gross – National Institutes of Health
    Author: John W. Glod – National Institutes of Health
    Author: William D. Figg, Sr. – National Cancer Institute
    Author: Priya Shankarappa – National Institutes of Health
    Author: Katherine E. Warren – Dana Farber Cancer Institute
    Author: Brigitte C. Widemann – National Institutes of Health
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-57 - The IGF-2 signaling pathway is a promising meningioma treatment target 
    Location: Exhibit Hall A/B
    Poster Presenter: Erik Uhlmann – Beth Israel Deaconess Medical Center
    Author: Rosalia Rabinovsky – Brigham and Women’s Hospital
    Author: Charles Mackel – Beth Israel Deaconess Hospital
    Author: Evgeny Deforzh – Brigham and Women's Hospital and Harvard Medical School
    Author: Rafael A. Vega – Beth Israel Deaconess Hospital
    Author: Hemant Varma – Beth Israel Deaconess Hospital
    Author: Anna M. Krichevsky – Brigham and Women's Hospital and Harvard Medical School
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-58 - Using MEK inhibitor to enhancement 5-ALA mediated sonodynamic therapeutic effect: a preclinical study
    Location: Exhibit Hall A/B
    Poster Presenter: Chiungyin Huang – Neuroscience Research Center, Chang Gung Memorial Hospital
    Author: Kuo-Chen Wei – New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation)
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-59 - Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Maite Verreault – Paris Brain Institute
    Author: Irma Segoviano Vilchis – Paris Brain Institute
    Author: Shai Rosenberg – Hebrew University Medical Center
    Author: Nolwenn Lemaire – Paris Brain Institute
    Author: Charlotte Schmitt – Paris Brain Institute
    Author: Jeremy Guehennec – Paris Brain Institute
    Author: Louis Royer-Perron – Pitie Salpetriere Hospital
    Author: Jean-Leon Thomas – Paris Brain Institute
    Author: Tukiet T Lam – Keck Biotechnology Resource Laboratory
    Author: Florent Dingli – Curie Institute
    Author: Damarys Loew – Curie Institute
    Author: Francois Ducray – Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Centre de Recherche en Cancérologie de Lyon
    Author: Sophie Paris – Paris Brain Institute
    Author: Catherine Carpentier – Paris Brain Institute
    Author: Yannick Marie – Paris Brain Institute
    Author: Florence Laigle-Donadey – Pitie Salpetriere Hospital
    Author: Audrey Rousseau – Paris Brain Institute
    Author: Natascha Pigat – Necker-Enfants Malades Institute
    Author: Florence Boutillon – Necker-Enfants Malades Institute
    Author: Franck Bielle – Pitie Salpetriere Hospital
    Author: Karima Mokhtari – Pitie Salpetriere Hospital
    Author: Stuart J Frank – University of Alabama at Birmingham
    Author: Aurelien de Reynies – Ligue Nationale Contre le Cancer
    Author: Khe Hoang-Xuan – Pitie Salpetriere Hospital
    Author: Marc Sanson – Pitie Salpetriere Hospital
    Author: Vincent Goffin – Necker-Enfants Malades Institute
    Author: Ahmed Idbaih – Sorbonne Université, AP-HP, ICM, Hôpital Universitaire La Pitié-Salpêtrière
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-60 - Overcoming the leptomeningeal seeding of medulloblastoma by targeting HSP70
    Location: Exhibit Hall A/B
    Poster Presenter: Seung Ah Choi – Seoul National University Hospital
    Author: Saehim Ha – Seoul National University Hospital
    Author: Seung-Ki Kim – Seoul National University Hospital
    Author: Do Won Hwang – THERABEST
    Author: Sekhoeun Heung – Seoul National University
    Author: Ji Hoon Phi – Seoul National University Hospital
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-61 - A multi-targeted approach to evaluate therapeutic selection and efficacy in preclinical GBM models. 
    Location: Exhibit Hall A/B
    Poster Presenter: Emily Eastwood – Certis Oncology Solutions
    Author: Bianca Carapia – Certis Oncology Solutions
    Author: Javier Rodriguez – Certis Oncology Solutions
    Author: Derrick Gorospe – Certis Oncology
    Author: Kristen Buck – Certis Oncology Solutions
    Author: Elizabeth Valencia – Certis Oncology
    Author: Bridget Corcoran – Certis Oncology Solutions
    Author: Yuan-Hung Chien – Certis Oncology Solutions
    Author: Raffaella Pippa – Certis Oncology
    Author: Warren Andrews – Certis Oncology Solutions
    Author: Long Do – Certis Oncology Solutions
    Author: Jonathan Nakashima – Certis Oncology Solutions
    Author: Jantzen Sperry – Certis Oncology Solutions
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-63 - MTA-cooperative PRMT5 inhibitors are efficacious in MTAP-deleted malignant peripheral nerve sheath tumor models
    Location: Exhibit Hall A/B
    Author: Dana Borcherding – Washington University in St. Louis
    Poster Presenter: Xiaochun Zhang – Washington University in St. Louis
    Author: Minjie Zhang – Tango Therapeutics
    Author: Himanshi Bhatia – Washington University in St. Louis
    Author: Yang Lyu – Washington University in St. Louis
    Author: Kevin He – Washington University in St. Louis
    Author: Liuzhan Yang – Washington University in St. Louis
    Author: Kuangying Yang – Washington University in St. Louis
    Author: Heather DiBenedetto – Tango Therapeutics
    Author: Alice Tsai – Tango Therapeutics
    Author: Alan Huang – Tango Therapeutics
    Author: John Maxwell – Tango Therapeutics
    Author: Kevin Cottrell – Tango Therapeutics
    Author: Kimberly Briggs – Tango Therapeutics
    Author: Angela C. Hirbe – Washington University in St. Louis
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-64 - Establishing a clinically relevant mouse model of mesenchymal glioblastoma for studying TME targeting treatments.
    Location: Exhibit Hall A/B
    Author: Kate Connor – Royal College of Surgeons in Ireland
    Poster Presenter: Kieron White – Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York Street, Dublin 2
    Author: James Clerkin – Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York Street, Dublin 2
    Author: Liam Shiels – Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York Street, Dublin 2
    Author: Kieron J. Sweeney – Department of Neurosurgery, Beaumont hospital, Dublin
    Author: Thomas Van Brussel – VIB Center for Cancer Biology, Leuven, Belgium
    Author: Ingrid Arijs – Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
    Author: Diether Lambrechts – Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium
    Author: Gautam Shankar – Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium
    Author: Frederik de Smet – Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium
    Author: Dieter Zopf – Research and Development, Preclinical Research Oncology, Bayer AG, Berlin, Germany.
    Author: Stephen Maher – Applied Radiation Therapy Trinity (ARTT), Discipline of Radiation Therapy, School of Medicine, Trinity St. James's Cancer Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland
    Author: Laure Marignol – Applied Radiation Therapy Trinity (ARTT), Discipline of Radiation Therapy, School of Medicine, Trinity St. James's Cancer Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland.
    Author: Patrick Dicker – Epidemiology & Public Health, Royal College of Surgeons in Ireland, Dublin 2
    Author: Jochen Prehn – Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York Street, Dublin 2
    Author: David O'Brien – Department of Neurosurgery, Beaumont hospital, Dublin
    Author: Annette T. Byrne – Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York Street, Dublin 2
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-65 - Identification of lomerizine as a potential anti-glioblastoma drug
    Location: Exhibit Hall A/B
    Poster Presenter: Toshiya Ichinose – kanazawa university
    Author: Shingo Tanaka – Department of Neurosurgery, Kanazawa University
    Author: Masashi Kinoshita – Department of Neurosurgery, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
    Author: Mitsutoshi Nakada – Department of Neurosurgery, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-68 - Systemic neutralization of IL6 sensitizes IDH-wildtype glioblastoma preclinical models to immune checkpoint inhibition
    Location: Exhibit Hall A/B
    Poster Presenter: Jacob S. Young – Department of Neurosurgery & Division of Neuro-Oncology, University of California San Francisco
    Author: Nam Woo Cho – UCSF
    Author: Calixto-Hope G. Lucas, Jr. – Department of Pathology, Johns Hopkins University
    Author: Kanish Mirchia – UCSF
    Author: Kyounghee Seo – UCSF
    Author: William C. Chen – University of California, San Francisco
    Author: Minh P. Nguyen – University of California, San Francisco
    Author: Arya Chen – UCSF
    Author: Joanna J. Phillips – University of California, San Francisco
    Author: Tomoko Ozawa – UCSF
    Author: Aparna Bhaduri – UCLA
    Author: Manish K. Aghi – University of California, San Francisco
    Author: Joseph DeRisi – UCSF
    Author: Mitchel S. Berger – University of California, San Francisco
    Author: Nicholas A. Butowski – University of California San Francisco
    Author: Matthew H. Spitzer – UCSF
    Author: David R. Raleigh – University of California, San Francisco
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-69 - Regulation of N1/N2 neutrophil phenotype by a manzamine-derived compound for brain tumor treatment
    Location: Exhibit Hall A/B
    Poster Presenter: Ya-Jui Lin – Chang Gung Medical Foundation
    Author: Chiungyin Huang – Neuroscience Research Center, Chang Gung Memorial Hospital
    Author: Kuo-Chen Wei – New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation)
    Author: Pin-Yuan Chen – Chang Gung Memorial Hospital at Keelung
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-70 - Utilizing oncolytic virotherapy as an approach to enhance neoantigen specific immune responses in glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Raziye Piranlioglu – Brigham and Women's Hospital/ Harvard Medical School
    Author: Ryujin Ahn – Massachusetts Institute of Technology
    Author: Anan Islam – Brigham and Women's Hospital/ Harvard Medical School
    Author: Michal Nowicki – Brigham and Women's Hospital/ Harvard Medical School
    Author: Alexander L. Ling – Brigham and Women's Hospital
    Author: Himanshu Soni – Brigham and Women's Hospita/ Harvard Medical School
    Author: Ved V. Ahuja – Brigham and Women's Hospita/ Harvard Medical School
    Author: William F. Goins – University of Pittsburg
    Author: Darrell J. Irvine – Massachusetts Institute of Technology
    Author: Forest M. White – Massachusetts Institute of Technology
    Author: Hiroshi Nakashima – Brigham and Women's Hospital/ Harvard Medical School
    Author: E. Antonio Chiocca – Brigham and Women's Hospital/ Harvard Medical School
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-71 - Automated and Multiplexed Combinatorial Drug Screening of FDA-Approved Drugs Identifies Potential Synergistic Drug Partners for the Treatment of Aggressive Meningiomas.
    Location: Exhibit Hall A/B
    Poster Presenter: Gerhard Jungwirth – Division of Experimental Neurosurgery, Department of Neurosurgery, Ruprechts-Karls-University Heidelberg, Heidelberg
    Author: Viktor Braun – Division of Experimental Neurosurgery, Department of Neurosurgery, Ruprechts-Karls-University Heidelberg, Heidelberg
    Author: Rolf Warta, Baden-Württemberg – University Hospital Heidelberg, Heidelberg, Germany
    Author: Amir Abdollahi – Department of Radiation Oncology, Ruprechts-Karl-University Heidelberg, Heidelberg, Germany
    Author: Andreas Unterberg – University Hospital Heidelberg, Heidelberg, Germany
    Author: Christel C. Herold-Mende – Division of Experimental Neurosurgery, Dept. of Neurosurgery, Heidelberg University Hospital,
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-72 - Targeted inhibition of three major proliferation pathways in glioblastoma induces senescence through a mitochondria-dependent mechanism
    Location: Exhibit Hall A/B
    Poster Presenter: Chrysiida Baltira – Netherlands Cancer Institute
    Author: Isabel Mayayo-Peralta – Netherlands Cancer Institute
    Author: Miriam Guillen-Navarro – Netherlands Cancer Institute
    Author: Ferhat Alkan – Netherlands Cancer Institute
    Author: Bram Thijssen – Netherlands Cancer Institute
    Author: Kimberley N. Pello – Netherlands Cancer Institute
    Author: Daria M. Fedorushkova – Netherlands Cancer Institute
    Author: Anna Their – Netherlands Cancer Institute
    Author: Joana Silva – Netherlands Cancer Institute
    Author: Fleur Jochems – Netherlands Cancer Institute
    Author: Onno Bleijerveld – Netherlands Cancer Institute
    Author: Hans Janssen – Netherlands Cancer Institute
    Author: William Faller – Netherlands Cancer Institute
    Author: Rene Bernards – Netherlands Cancer Institute
    Author: Mark C. de Gooijer – Netherlands Cancer Institute
    Author: Olaf van Tellingen – Netherlands Cancer Institute
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-73 - In vivo effects of EpCAM-directed CAR T cells in combination with PD-1 checkpoint blockade in lung cancer brain metastasis.
    Location: Exhibit Hall A/B
    Poster Presenter: Jens Blobner – Department of Neurosurgery, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Laura Dengler – Department of Neurosurgery, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Constantin Eberle – Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Julika J. Herold – Department of Neurosurgery, University Hospital of the Ludwig-Maximilians-University Munich
    Author: Tao Xu – Department of Neurosurgery, LMU University Hospital, Ludwig Maximilians University (LMU), 81377 Munich, Germany
    Author: Nico Teske – Department of Neurosurgery, LMU University Hospital Munich
    Author: Philipp Karschnia – Dept. of Neurosurgery, Ludwig Maximilians University (LMU) Munich,
    Author: Hellen Ishikawa-Ankerhold – Department of Medicine I, Ludwig-Maximilians-University School of Medicine, Munich, Germany
    Author: Marion Subklewe – Department of Medicine III, Ludwig-Maximilians-University School of Medicine, Munich, Germany
    Author: Niklas Thon – Department of Neurosurgery, University Hospital, LMU Munich
    Author: Joerg-Christian Tonn – Department of Neurosurgery, University Hospital, LMU Munich
    Author: Veit Buchholz – Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany
    Author: Louisa von Baumgarten – Dept. of Neurosurgery, Ludwig Maximilians University (LMU) Munich,
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-74 - Tumor pharmacokinetics and pharmacodynamics in patient-derived xenograft models of glioblastoma treated with the PRMT5 inhibitor SKL27969
    Location: Exhibit Hall A/B
    Poster Presenter: An-Chi Tien – Ivy Brain Tumor Center
    Author: Tigran Margaryan – Ivy Brain Tumor Center
    Author: Jennifer Molloy – Ivy Brain Tumor Center
    Author: James McNamara – Ivy Brain Tumor Center
    Author: William L. Knight – Ivy Brain Tumor Center/University of Arizona College of Medicine
    Author: Raymond Hon – Ivy Brain Tumor Center
    Author: Zorana Opachich – Ivy Brain Tumor Center
    Author: Ernesto Luna Melendez – Ivy Brain Tumor Center
    Author: Mackenna Elliott – Ivy Brain Tumor Center
    Author: Connor White – Ivy Brain Tumor Center
    Author: Nader Sanai – Barrow Neurological Institute
    Author: Artak Tovmasyan – Barrow Neurological Institute
    Author: Shwetal Mehta – Ivy Brain Tumor Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-76 - Translational Barriers in 5-ALA Photodynamic Therapy for Gliomas: A Systematic Review of the In Vivo Landscape and Future Directions for Clinical Applicability
    Location: Exhibit Hall A/B
    Poster Presenter: Debarati Bhanja – Penn State Hershey Medical Center
    Author: Hannah Wilding – Penn State Hershey Medical Center
    Author: Leonardo Jose Monteiro De Macedo Filho – Penn State Hershey Medical Center
    Author: Angel R. Baroz – Penn State College of Medicine
    Author: Mara Trifoi – Penn State College of Medicine
    Author: Ganesh Shenoy – Penn State College of Medicine
    Author: Becky Slage-Webb – Penn State University
    Author: Daniel Hayes – Pennsylvania State University
    Author: Yasaman Soudagar – Neurescence, Inc.
    Author: James R. R. Connor – Penn State University
    Author: Alireza Mansouri – Penn State Hershey Medical Center
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-77 - Extended half-life IL-2 synergizes with α-PD-1 for treatment of preclinical murine glioblastoma models
    Location: Exhibit Hall A/B
    Poster Presenter: Carley A. Owens – Mayo Clinic
    Author: Zachariah P. Tritz – Mayo Clinic
    Author: Katayoun Ayasoufi – Duke University
    Author: Delaney M. Wolf – Mayo Clinic
    Author: Ian F. Parney – Mayo Clinic
    Author: Michael Hanson – Mayo Clinic
    Author: Jin Fang – Mayo Clinic
    Author: Aaron J. Johnson – Mayo Clinic
    Author: Jian L. Campian – Mayo Clinic
    Author: Cori E. Fain – Mayo Clinic
    Author: Benjamin Himes – Montefiore/Albert Einstein College of Medicine
    Author: Courtney Malo – Mayo Clinic
    Author: Emma Goddery – Moderna
    Author: Lila Yokanovich – Mayo Clinic
    Author: Chensu Wang – MIT
    Author: Richard Vile – Mayo Clinic
    Author: Kelly Moynihan – The Hertz Foundation
    Author: Darrell J. Irvine – Massachusetts Institute of Technology
    Author: Rosa mercano – Mayo Clinic
    Author: Dane Wittrup – MIT
    Author: Mark Maynes – Mayo Clinic
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-79 - A novel anti-Galectin-3 antibody therapeutic synergizes with temozolomide in preclinical models to diminish tumor growth, decrease migration, and prolong survival
    Location: Exhibit Hall A/B
    Poster Presenter: Anne Marie Barrette – TrueBinding
    Author: Krutika Deshpande – TrueBinding
    Author: Bailey McDonald – TrueBinding
    Author: Marvin Cadiente – TrueBinding
    Author: Xi Wang – TrueBinding
    Author: Dongxu Sun – TrueBinding
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-82 - The role of PTEN and epigenetic kinome programming in EGFR TKI response in glioblastoma
    Location: Exhibit Hall A/B
    Poster Presenter: Julia K. Ziebro – University of Alabama at Birmingham
    Author: Abigail K. Shelton – University of Alabama at Birmingham
    Author: Erin Smithberger – University of Alabama at Birmingham
    Author: Benjamin Lin – University of Alabama at Birmingham
    Author: Kasey R. Skinner – University of Alabama at Birmingham
    Author: Allie Stamper – University of Alabama at Birmingham
    Author: Ryan E. Bash – University of Alabama at Birmingham
    Author: Frank B. Furnari – University of California, San Diego
    Author: Christopher R. Miller – University of Alabama at Birmingham
    Preclinical Experimental Therapeutics
  • Friday, Nov 17th
    7:30 PM – 9:30 PM PT
    EXTH-85 - EphA3 CART: Dual Targeting of Glioblastoma and Tumor Microenvironment
    Location: Exhibit Hall A/B
    Poster Presenter: Michael W. Ruff – Mayo Clinic
    Author: Ekene Ogbodo – Mayo Clinic
    Author: Elizabeth Siegler – Mayo Clinic
    Author: Leo Sakemura – Mayo Clinic
    Author: Jann N. Sarkaria – Mayo Clinic
    Author: Saad Kenderian – Mayo Clinic
    Preclinical Experimental Therapeutics
  • Saturday, Nov 18th
    11:15 AM – 11:25 AM PT
    EXTH-16 - Development of intrathecal (IT) drug delivery platform to cure breast cancer (BC) leptomeningeal disease (LMD) by peptide-pulsed type 1 conventional dendritic cell (cDC1) vaccine in preclinical model
    Location: Room 109-110
    Oral Abstract Presenter: Vincent Law – H. Lee Moffitt Cancer Center and Research Institute
    Author: Colin Snyder – H. Lee Moffitt Cancer Center and Research Institute
    Author: Lauren Macaisa – H. Lee Moffitt Cancer Center and Research Institute
    Author: Saurabh Garg – H. Lee Moffitt Cancer Center and Research Institute
    Author: Brian Czerniecki – Moffitt Cancer Center
    Author: Peter Forsyth – Moffitt Cancer Center
    Preclinical Experimental Therapeutics
  • Saturday, Nov 18th
    11:45 AM – 11:50 AM PT
    EXTH-42 - Preclinical investigation of a novel brain penetrant MEK inhibitor to target brain metastasis
    Location: Room 109-110
    Oral Abstract Presenter: Erika Yamazawa – Massachusetts General Hospital
    Author: Naema Nayyar – Massachusetts General Hospital
    Author: Nazanin Ijad – Massachusetts General Hospital
    Author: Consuelo Torrini – Massachusetts General Hospital
    Author: Magali De Sauvage – Massachusetts General Hospital
    Author: Christian Migliarese – Massachusetts General Hospital
    Author: Elizabeth J. Summers – Massachusetts General Hospital
    Author: Braxton Marion – Massachusetts General Hospital/Harvard Medical School
    Author: Catherine Lee – Kinnate Biopharma
    Author: Rowena Suriben – Kinnate Biopharma
    Author: Michelle Perez – Kinnate Biopharma
    Author: Ben Powell – Kinnate Biopharma
    Author: Nichol Miller – Former Kinnate employee
    Author: Brooke Grandinetti – Kinnate Biopharma
    Author: Hiroaki Wakimoto – Harvard Medical School
    Author: Priscilla K. Brastianos – Massachusetts General Hospital/Harvard Medical School
    Preclinical Experimental Therapeutics
  • Saturday, Nov 18th
    4:45 PM – 4:50 PM PT
    EXTH-17 - Targeting CTPS1 and nucleotide biosynthesis pathways as a novel therapeutic approach in MYC-amplified medulloblastoma
    Location: Room 109-110
    Author: Matthew Hathaway – Seattle Childrens Research Institute
    Author: Hawa Jagana – Seattle Childrens Research Institute
    Author: Michael Meechan – Seattle Childrens Research Institute
    Author: Ashmitha Rajendran – Seattle Childrens Research Institute
    Author: Barbara Slusher – Johns Hopkins
    Oral Abstract Presenter: Myron Evans, II – Seattle Childrens Research Institute
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    10:25 AM – 10:35 AM PT
    EXTH-78 - CRISPRoff epigenome editing and functional genomics define mediators of chemotherapy resistance in glioblastoma
    Location: Room 109-110
    Author: Katie Lin – University of California, San Francisco
    Author: Laine Goudy – University of California, San Francisco
    Author: Joanna Pak – UCSF
    Author: Kyla Foster – University of California, San Francisco
    Author: Emily Payne – UCSF
    Author: Tomoko Ozawa – UCSF
    Author: John F. de Groot – University of California, San Francisco
    Author: Harish N. Vasudevan – UCSF
    Author: David R. Raleigh – University of California, San Francisco
    Author: Luke Gilbert – University of California, San Francisco
    Author: Mitchel S. Berger – University of California, San Francisco
    Oral Abstract Presenter: John Liu – UCSF
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    10:45 AM – 10:55 AM PT
    EXTH-81 - Re-expression of CXCL9 following adeno-associated virus (AAV) transgene delivery transforms the immunological landscape of glioblastoma, sensitizing tumors to PD-1 immune checkpoint blockade (ICB)
    Location: Room 109-110
    Oral Abstract Presenter: Christina A. von Roemeling – University of Florida
    Author: Oleg Yegorov – University of Florida
    Author: Changlin Yang – University of Florida
    Author: Rylynn Russell – University of Florida
    Author: Savannah Carpenter – University of Florida
    Author: Vrunda Trivedi – University of Florida
    Author: Alisha Bhatia – University of Florida
    Author: Bently Doonan – University of Florida
    Author: Todd Golde – Emory University
    Author: Duane A. Mitchell – University of Florida
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    10:55 AM – 11:05 AM PT
    EXTH-34 - Local delivery of an IL-15 superagonist using a replicating retrovirus syngerizes with temozolomide to increase lymphocyte infiltration and survival in two poorly immunogenic glioblastoma mouse models
    Location: Room 109-110
    Oral Abstract Presenter: Alexander F. Haddad – Department of Neurosurgery & Division of Neuro-Oncology, University of San Francisco
    Author: Jordan Spatz – UCSF
    Author: Atul Saha – UCSF
    Author: Megan L. Montoya – UCSF
    Author: Sara A. Collins – University of California, San Francisco
    Author: Sabraj Gill – University of California San Fransisco
    Author: Elaina J. Wang – UCSF
    Author: Pavlina Chuntova – Department of Neurological Surgery, University of California San Francisco
    Author: Diana Salha – UCSF
    Author: Jacob S. Young – Department of Neurosurgery & Division of Neuro-Oncology, University of California San Francisco
    Author: Noriyuki Kasahara – University of California, San Francisco
    Author: Manish K. Aghi – University of California, San Francisco
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    11:15 AM – 11:20 AM PT
    EXTH-28 - Isocitrate dehydrogenase mutations predict sensitivity to histone deacetylase inhibition and enhanced histone acetylation dynamics only in the context of glioma
    Location: Room 109-110
    Oral Abstract Presenter: Thomas K. Sears – Northwestern University
    Author: Michael Drumm – Department of Neurological Surgery, Northwestern University, Chicago, Illinois
    Author: Wenxia Wang – Northwestern University
    Author: Craig Horbinski – Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    11:20 AM – 11:25 AM PT
    EXTH-03 - A VEGF+ subpopulation of Schwann cells drives vestibular schwannoma tumorigenesis
    Location: Room 109-110
    Oral Abstract Presenter: David Asuzu – National Institute of Neurological Disorders and Stroke
    Author: Stefan Stoica – Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH
    Author: Liyam Laraba – University of Plymouth
    Author: Martin Arhin – National Institute of Neurological Disorders and Stroke
    Author: Jasleen Gandhi – National Institute of Neurological Disorders and Stroke
    Author: Dustin Mullaney – National Institute of Neurological Disorders and Stroke
    Author: Debjani Mandal – National Institute of Neurological Disorders and Stroke
    Author: David Parkinson – Plymouth University
    Author: Prashant Chittiboina – National Institute of Neurological Disorders and Stroke
    Preclinical Experimental Therapeutics
  • Sunday, Nov 19th
    11:30 AM – 11:35 AM PT
    EXTH-46 - Schlafen11 is a powerful biomarker of chemosensitivity in medulloblastomas
    Location: Room 121-122
    Oral Abstract Presenter: Manabu Natsumeda – Niigata University Brain Research Institute
    Author: Satoshi Nakata – Gunma University
    Author: Junko Murai – Ehime University
    Author: Takahashi Haruhiko – Niigata University Brain Research Institute
    Author: Masayasu Okada – Niigata University Brain Research Institute
    Author: Jun Watanabe – University of Alabama-Birmingham
    Author: Yoshihiro Tsukamoto – Niigata University Brain Research Institute
    Author: Kensuke Tateishi – Yokohama City University
    Author: Satoru Osuka – University of Alabama-Birmingham
    Author: Eric Raabe – Johns Hopkins University
    Author: Celio Pouponnot – Institut Curie
    Author: Yves Pommier – National Institutes of Health
    Author: Makoto Oishi – Niigata University Brain Research Institute
    Author: Akiyoshi Kakita – Niigata University Brain Research Institute
    Author: Charles G. Eberhart – Johns Hopkins University
    Preclinical Experimental Therapeutics