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Friday, Nov 17th
4:25 PM – 4:35 PM PT
TMET-02 - Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
Location: Room 121-122
Author: Sriram Venneti – University of Michigan
Author: Abed Rahman Kawakibi – University of Michigan
Author: Sunjong Ji – University of Michigan
Author: Sebastian M. Waszak – École Polytechnique Fédérale de Lausanne (EPFL)
Author: Stefan R. Sweha – Memorial Sloan Kettering Cancer Center
Author: Mateus Mota – University of Michigan
Author: Matthew Pun – University of Michigan
Author: Akash Deogharkar – University of Michigan
Author: Chan Chung – Daegu Gyeongbuk Institute of Science and Technology
Author: Rohinton S. Tarapore – Chimerix, Inc.
Author: Samuel Ramage – Chimerix, Inc.
Author: Patrick Y. Wen – Dana-Farber Cancer Institute
Author: Isabel Arrillaga-Romany – Massachusetts General Hospital
Author: Hugh Garton – University of Michigan
Author: Andrea T. Franson – University of Michigan
Author: Jonathan Schwartz – Mayo Clinic
Author: Rajan Jain – NYU Langone Health
Author: Sophie L. Mottl – University of Oslo
Author: Rodrigo Cartaxo – University of Michigan
Author: Vishal John – University of Michigan
Author: Dana Messinger – University of Michigan
Author: Tingting Qin – University of Michigan
Author: Erik Peterson – University of Michigan
Author: Peter Sajjakulnukit – University of Michigan
Author: Alexander R. Judkins – University of Southern California
Author: Daniel R. Wahl – University of Michigan
Author: Costas A. Lyssiotis – University of Michigan
Author: Daniel de la Nava – Clínica Universidad de Navarra
Author: Martha M. Alonso – Clínica Universidad de Navarra
Author: Ryan J. Duchatel – University of Newcastle
Author: Matthew D. Dun – University of Newcastle
Author: Jason E. Cain – Hudson Institute of Medical Research
Author: Li Jiang – Dana-Farber/Boston Children’s Cancer and Blood Disorder Center
Author: Mariella G. Filbin – Dana-Farber/Boston Children’s Cancer and Blood Disorder Center
Author: Lili Zhao – University of Michigan
Author: Chandan Kumar-Sinha – University of Michigan
Author: Rajen Mody – University of Michigan
Author: Arul Chinnaiyan – University of Michigan
Author: Ryo Kurokawa – University of Tokyo
Author: Drew Pratt – National Cancer Institute
Author: Viveka N. Yadav – Children’s Mercy Research Institute
Author: Jacques Grill – Université Paris-Saclay
Author: Cassie Kline – Children's Hospital of Philadelphia
Author: Sabine Mueller – University of California, San Francisco
Author: Adam Resnick – Children's Hospital of Philadelphia
Author: Javad Nazarian – University Children’s Hospital Zurich
Author: Joshua E. Allen – Chimerix, Inc.
Author: Yazmin Odia – Miami Cancer Institute, part of Baptist Health South Florida
Author: Sharon L. Gardner – NYU
Oral Abstract Presenter: Carl J. Koschmann – University of Michigan
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-01 - Therapeutic targeting of crosstalk between mitochondrial fitness and cell adhesion/migration in diffuse midline glioma (DMG)
Location: Exhibit Hall A/B
Author: Rodrigo Cartaxo – University of Michigan
Author: Sunjong Ji – University of Michigan
Poster Presenter: Kallen Schwark – University of Michigan
Author: Carl J. Koschmann – University of Michigan
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-04 - Sensitizing DIPGs to antifolates: A preclinical study on purine biosynthesis targets
Location: Exhibit Hall A/B
Poster Presenter: Ian Mersich – Cincinnati Children's Hospital
Author: Sunny Congrove – Cincinnati Children's Hospital
Author: Biplab Dasgupta – Cincinnati Children's Hospital
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-06 - Metabologenomic Characterization Uncovers Heterogeneity Amongst IDH Mutant
Location: Exhibit Hall A/B
Poster Presenter: Andrew Ajisebutu – UHN
Author: Farshad Nassiri – University of Toronto
Author: Yasin Mamatjan – Thompson Rivers University
Author: Vikas Patil – UHN
Author: Justin Wang – University of Toronto
Author: Mathew R. Voisin – University of Toronto
Author: Sheila Mansouri – Princess Margaret Cancer Research Tower
Author: Gelareh Zadeh – University Health Network, Toronto Western Hospital
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-07 - Metabolic risk factors and outcomes in patients with glioblastoma
Location: Exhibit Hall A/B
Author: John Paul Aboubechara – Department of Neurology, University of California, Davis, Sacramento, CA
Poster Presenter: Orwa Aboud – University of California Davis
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-08 - Elongation control of mRNA translation drives Group 3 medulloblastoma adaptation to nutrient deprivation
Location: Exhibit Hall A/B
Poster Presenter: Alberto Delaidelli – BC Cancer
Author: Betty Yao – BC Cancer
Author: Fares Burwag – BC Cancer
Author: Jessica Oliveira de Santis – BC Cancer
Author: Yue Zhou Huang – BC Cancer
Author: Haifeng Zhang – BC Cancer
Author: Gian Luca Negri – BC Genome Sciences Center
Author: Christopher Hughes – BC Cancer
Author: Gabriel Leprivier – University of Dusseldorf
Author: Poul Sorensen – BC Cancer
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-10 - Investigating how glioblastoma tumour cells exploit their metabolic microenvironment
Location: Exhibit Hall A/B
Poster Presenter: Chloe Shard – Centre for Cancer Biology, University of South of Australia
Author: Rebecca Ormsby – Flinders Health and Medical Research Institute
Author: Santosh Poonnoose – Flinders Medical Centre
Author: John Toubia – Centre for Cancer Biology, University of South of Australia
Author: Paul Trim – South Australian Health and Medical Research Institute
Author: Lisa Ebert – Centre for Cancer Biology, University of South of Australia
Author: Ashwini Patil – Combinatics Inc.
Author: Guillermo Gomez – Centre for Cancer Biology, University of South of Australia
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-11 - Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery
Location: Exhibit Hall A/B
Poster Presenter: Satoshi Suehiro – Department of Neurosurgery, Ehime University Graduate School of Medicine
Author: Yoshihiro Ohtsuka – Ehime University Graduate School of Medicine
Author: Akihiro Inoue – Department of Neurosurgery, Ehime University Graduate School of Medicine
Author: Takanori Ohnishi – Department of Neurosurgery, Washoukai Sadamoto Hospital
Author: Daisuke Yamashita – Ehime University
Author: Masahiro Nishikawa – Department of Neurosurgery, Ehime University Graduate School of Medicine
Author: Hideaki Watanabe – Department of Neurosurgery, Ehime University Graduate School of Medicine
Author: Takeharu Kunieda – Department of Neurosurgery, Ehime University Graduate School of Medicine
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-13 - DNA damage signaling activates GTP synthesis to promote glioblastoma treatment resistance
Location: Exhibit Hall A/B
Poster Presenter: Andrew J. Scott – University of Michigan
Author: Alexandra O'Brien – University of Michigan
Author: Weihua Zhou – University of Michigan
Author: Jie Xu – University of Michigan
Author: Sravya Palavalasa – University of Michigan
Author: Ayesha Kothari – University of Michigan
Author: Kari Wilder-Romans – University of Michigan
Author: Angelica Lin – University of Michigan
Author: Zitong Zhao – University of Michigan
Author: Annabel Yang – University of Michigan
Author: Navyateja Korimerla – University of Michigan
Author: Erik Peterson – University of Michigan
Author: John Yang – University of Michigan
Author: Li Zhang – University of Michigan
Author: Anthony Andren – University of Michigan
Author: Sriram Chandrasekaran – University of Michigan
Author: Sriram Venneti – University of Michigan
Author: Jason Heth – University of Michigan
Author: Yoshie Umemura – Ivy Brain Tumor Center at Barrow Neurological Institute
Author: Nathan Qi – University of Michigan
Author: John Woulfe – Ottawa Hospital Research Institute
Author: Meredith Morgan – University of Michigan
Author: Theodore S. Lawrence – University of Michigan
Author: Wajd Al-Holou – University of Michigan
Author: Costas A. Lyssiotis – University of Michigan
Author: Daniel R. Wahl – University of Michigan
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-14 - Probing TCA cycle activity in H3WT and H3K27M-altered diffuse midline gliomas
Location: Exhibit Hall A/B
Author: Omkar B. Ijare – Houston Methodist Hospital
Author: Jackson Roberson – Houston Methodist
Author: Sushmita Kumar – LAWRENCE E. ELKINS HIGH SCHOOL/Houston Methodist Hospital
Author: Rishith Ramamurthy – Houston Methodist
Author: David S. S. Baskin – Houston Methodist Hospital
Poster Presenter: Kumar Pichumani – Houston Methodist Hospital
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-17 - Leveraging metabolic vulnerabilities induced by TERT expression for glioblastoma therapy in vivo.
Location: Exhibit Hall A/B
Author: Suresh Udutha – University of California San Francisco
Author: Celine Taglang – University of California San Francisco
Author: Georgios Batsios – University of California, San Francisco
Author: Anne Marie Gillespie – UCSF
Poster Presenter: Pavithra Viswanath – University of California, San Francisco
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-18 - Metabolomic approach to identification of prognostic biomarkers of glioblastoma
Location: Exhibit Hall A/B
Poster Presenter: John Paul Aboubechara – Department of Neurology, University of California, Davis, Sacramento, CA
Author: Yin Allison Liu – Department of Ophthalmology
Author: Oliver Fiehn – West Coast Metabolomics Center
Author: Ruben Fragoso – 5. Department of Radiation Oncology, University of California Davis
Author: Han Lee – University of California, Davis
Author: Jonathan Riess – Department of Internal Medicine, Division of Hematology and Oncology, University of California, Davis
Author: Rawad Hodeify – Department of Biotechnology, School of Arts and Sciences, American University of Ras Al Khaimah
Author: Orin Bloch – Department of Neurological Surgery, University of California Davis
Author: Orwa Aboud – University of California Davis
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-19 - Targeting amino acid metabolic vulnerabilities in IDH-mutant and IDH-wildtype gliomas
Location: Exhibit Hall A/B
Poster Presenter: Shigeo Ohba – Fujita Health University
Author: Takao Teranishi – Fujita Health University
Author: Akiyoshi Hirayama – Keio　University
Author: Keisuke Hitachi – Fujita Health University
Author: Hisateru Yamaguchi – Fujita Health University
Author: Manabu Natsumeda – Niigata University Brain Research Institute
Author: Kensuke Tateishi – Yokohama City University
Author: Russell O. Pieper – University of California, San Francisco
Author: Yuichi Hirose – Fujita Health University School of Medicine
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-20 - Targeting links between methionine metabolism and DNA repair to improve GBM therapy
Location: Exhibit Hall A/B
Author: Navyateja Korimerla – University of Michigan
Author: Kari Wilder-Romans – University of Michigan
Author: Jie Xu – University of Michigan
Author: Isra Haq – University of Michgan
Author: Peter Kalev – Agios Pharmaceuticals
Author: Nathan Qi – University of Michigan
Author: Charles Evans – University of Michigan
Author: Maureen Kachman – University of Michigan
Author: Weihua Zhou – University of Michigan
Author: Andrew J. Scott – University of Michigan
Author: Ayesha Kothari – University of Michigan
Author: Angelica Lin – University of Michigan
Author: Alexandra O'Brien – University of Michigan
Author: Sravya Palavalasa – University of Michigan
Author: Erik Peterson – University of Michigan
Author: Marc L Hyer – servier pharmaceuticals
Author: Katya Marjon – servier pharmaceuticals
Author: Costas A. Lyssiotis – University of Michigan
Author: Taryn Sleger – servier pharmaceuticals
Poster Presenter: Daniel R. Wahl – University of Michigan
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-21 - Proton magnetic resonance spectroscopy (¹H MRS) for the diagnosis of aggressive meningiomas with recurrence potential
Location: Exhibit Hall A/B
Poster Presenter: Omkar B. Ijare – Houston Methodist Hospital
Author: David S. S. Baskin – Houston Methodist Hospital
Author: Suzanne Powell – Houston Methodist Hospital
Author: Kumar Pichumani – Houston Methodist Hospital
Tumor Metabolism
Friday, Nov 17th
7:30 PM – 9:30 PM PT
TMET-22 - Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations
Location: Exhibit Hall A/B
Poster Presenter: Nikita Choudhary – University of California San Fransisco
Author: Joseph Garcia – University of California San Fransisco
Author: Erin Akins – University of California, Berkeley
Author: Saket Jain – University of California San Fransisco
Author: Kayla Wolf – University of California, Berkeley
Author: Jason Zhang – University of California, Berkeley
Author: Meeki Lad – University of California San Fransisco
Author: Poojan Shukla – University of California San Fransisco
Author: Sabraj Gill – University of California San Fransisco
Author: Will Carson – University of California San Fransisco
Author: Luis Carrete – University of California San Fransisco
Author: Allison C. Zheng – University of California San Fransisco
Author: Sanjay Kumar – University of California, Berkeley
Author: Manish K. Aghi – University of California, San Francisco
Tumor Metabolism
Saturday, Nov 18th
3:45 PM – 3:55 PM PT
TMET-12 - CDKN2A Deletion Remodels Lipid Metabolism to Prime Glioblastoma for Ferroptosis
Location: Room 109-110
Oral Abstract Presenter: Jenna K. Minami – UCLA
Author: Danielle Morrow – UCLA
Author: Nicholas A. Bayley – UCLA
Author: Elizabeth Grace Fernandez – UCLA
Author: Jennifer J. Salinas – UCLA
Author: Christopher Tse – UCLA
Author: Henan Zhu – UCLA
Author: Baolong Su – UCLA
Author: Alessandro Sammarco – UCLA
Author: Linda M. Liau – UCLA
Author: Thomas G. Graeber – UCLA
Author: Kevin J. Williams – UCLA
Author: Timothy F. Cloughesy – University of California Los Angeles
Author: Scott J. Dixon – Stanford University
Author: Steven J. Bensinger – UCLA
Author: David A. Nathanson – UCLA
Tumor Metabolism
Saturday, Nov 18th
3:55 PM – 4:05 PM PT
TMET-03 - Reprogramming of glioblastoma glucose metabolism fuels tumor growth
Location: Room 109-110
Oral Abstract Presenter: Andrew J. Scott – University of Michigan
Author: Anjali mittal – University of Michigan
Author: Wajd Al-Holou – University of Michigan
Author: Sravya Palavalasa – University of Michigan
Author: Baharan Meghdadi – University of Michigan
Author: Alexandra O'Brien – University of Michigan
Author: Weihua Zhou – University of Michigan
Author: Annabel Yang – University of Michigan
Author: Zitong Zhao – University of Michigan
Author: Angelica Lin – University of Michigan
Author: Vijay Tarnal – University of Michigan
Author: Costas A. Lyssiotis – University of Michigan
Author: Deepak Nagrath – University of Michigan
Author: Daniel R Wahl – University of Michigan
Tumor Metabolism
Saturday, Nov 18th
4:15 PM – 4:25 PM PT
TMET-09 - Sex differences in serine-derived glycine biosynthesis drive responses to combined nutrient deprivation and pharmacological inhibition in GBM
Location: Room 109-110
Author: Jianyun Lu – Washington University School of Medicine
Oral Abstract Presenter: Camryn Tyler Marquez – Washington University School of Medicine
Author: Jasmin Sponagel – Washington University School of Medicine
Author: Prakash Chinnaiyan – Oakland University William Beaumont School of Medicine
Author: Joshua B. B. Rubin – Washington University School of Medicine
Author: Joseph E. Ippolito – Washington University School of Medicine
Tumor Metabolism