University of Miami
Coral Gables, Florida, United States
Dr. Anna Lasorella, MD is Professor of Biochemistry and Molecular Biology at University of Miami, Miller School of Medicine, where she moved in 2022 after she was a professor of Pediatrics and Pathology and Cell biology at Columbia University. She runs a successful program that combines the use of protein biochemistry, mouse models, and integrative systems biology to pursuit normal and pathological cellular functions of glioma-related genes. In line with her training as pediatric neuro-oncologist, the common thread running through her research activities is her interest in identifying and characterizing drivers of malignancy in the brain that are linked to developmental processes and can inspire novel therapeutic strategies for malignant glioma, including glioma occurring in individuals affected by neurofibromatosis 1. Her work has led to several landmark publications (Carro et al. Nature 2010; Singh et al. Science 2012; Frattini et al. Nature Genetics 2013; Lee et al. Nature 2016; Frattini et. al. Nature 2018; D’Angelo et. al. Nature Medicine 2019; Garofano et al. Nature Cancer, 2021; Migliozzi et al. Nature Cancer, 2023; Ko et al. Cancer Discovery, 2023). More recent research interest focuses on trans-disciplinary approaches combining data science and computational pharmacology to develop experimentally validated pipelines for personalized cancer therapeutics. As the leader of the Precision Cancer Initiative at the Sylvester Comprehensive Cancer Center of the University of Miami she organizes resources and infrastructures to develop investigational tools to dependencies and targets for sporadic and syndromic malignant glioma.
