Uppsala University
Uppsala, United States
Cecilia Krona is a scientist with an MSc in molecular biology and a Ph.D. in clinical genetics from the University of Gothenburg, Sweden, focusing on identifying a potential tumor suppressor for development of neuroblastoma tumors. Following her Ph.D., she joined the laboratory of Don W Cleveland at the Ludwig Institute at the University of California San Diego, where she investigated cell cycle regulators as targets for brain tumor therapy. Cecilia then joined the Kogner group at the medical faculty of the Karolinska Institute to establish models for medulloblastoma research. In 2014, Cecilia joined the Nelander group at Uppsala University in 2014, where she has since worked as a senior scientist and project coordinator on several multi-disciplinary systems biology projects focusing on neural cancers.
Her work currently explores drivers of glioblastoma invasion and applications of molecular and genomic technologies to validate therapeutic targets of high-grade glioma identified through an integrated mapping of molecular data to specific invasion routes in vivo. She is particularly interested in understanding the molecular triggers and activators of invasion and how they are regulated. To tackle this question, the Nelander group rely on state-of-the-art technologies enabling studies of glioma progression and invasion involving advanced live imaging, bulk- and single-cell transcriptomics, CRISPR/Cas9 editing, cellular assays to determine drug response and underlying cellular mechanisms, mathematical modeling, and in vivo validation of targeted therapies against neural cancer.
