UCSF
San Francisco, California, United States
Dr. Wiencke received his Ph.D. in Pathology and Laboratory Medicine and completed post-doctoral training in Radiobiology and Human Genetics at the University of California San Francisco (UCSF). He established the UCSF Laboratory for Molecular Epidemiology in the Department of Epidemiology and Biostatistics and served as its director. The laboratory supports both constitutive and tumor related genetic and epigenetic molecular analyses in population based human cancer studies. Since 2004 Dr. Wiencke has co-directed the Laboratory for Neuro and Molecular Epidemiology within the Department of Neurological Surgery. Dr. Wiencke is the co-PI of a large glioma case control study that was funded by NCI continuously for 21 years. He is the PI of an R01 that develops new biomarkers to predict survival in glioma and other cancer types. He is the co-PI of a UCSF brain tumor SPORE project exploring immune factors associated with brain tumor survival. The main focus of Dr. Wiencke’s research is DNA methylation as a biomarker of immune cell concentrations in peripheral blood and tumor specimens using cell specific DNA methylation, an approach called immunomethylomics. This work in collaboration with Drs. Houseman, Kelsey, Koestler and Christensen has included the first papers using methylation arrays to interrogate immune cell subtypes.
