University of Florida
Gainesville, Florida, United States
Dr. Deleyrolle leads a brain cancer stem cell research group and is an Assistant Professor in the Department of Neurosurgery at the University of Florida. He is also an Adjunct Faculty Member in the Department of Neuroscience and member of the Cancer Center at the University of Florida.
Dr. Deleyrolle was born and raised in France, where he received a B.S. and M.S. from the University of Grenoble, France in 2001. He completed his Ph.D. in 2006 at the Institute for Neuroscience of the University of Montpellier in France with Pr. Alain Privat. His work focused on investigating the molecular determinants regulating the differentiation of spinal cord neural stem cells. Dr. Deleyrolle then completed post-doctoral fellowships in 2011 at the Queensland Brain Institute of the University of Queensland, Australia and the McKnight Brain Institute of the University of Florida with Dr. Brent Reynolds where he focused on developing and enabling innovative technologies to identify and measure stem cell and cancer stem cell activities. In 2016, Dr. Deleyrolle joined the Preston A. Wells, Jr. Center for Brain Tumor Therapy at the University of Florida as a principal investigator and his work focuses on the following lines of investigation: i) investigate metabolic heterogeneity in brain tumors, ii) develop and assess the effect of experimental metabolic strategies to treat brain cancer, iii) investigate and exploit metabolic communications in the tumor microenvironment, iv) metabolic engineering of T cells to improve immunotherapy, and v) evaluate the immunogenicity of slow-cycling tumor cell RNA in the context of anti-cancer vaccines.