Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University
Taipei, Taipei, Taiwan (Republic of China)
Zhen-Jie Tong (童振傑)
PhD candidate, Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University
Address: No. 155,Sec. 2, Linong St.
Beitou District, Taipei
112304, Taiwan, R.O.C
Email: zhenjietong723@gmail.com
Phone: 02-28267000 #66433
PROFILE
The research field of the laboratory I joined is cancer and metabolic diseases, focusing on the pathological effect of endotoxin, Acrolein. My major topic is to explore the immunomodulation of neutrophils induced by acrolein in glioma progression for my PhD degree.
EDUCATION
National Yang Ming Chiao Tung University (NYCU)
Sep, 2020 ~ present; Ph.D. degree, Major: Pharmacology
National Yang Ming University (NYMU)
Sep, 2017 ~ Aug, 2020; Master degree, Major: Anatomy & Cell Biology
PUBLICATIONS
1. Acrolein produced by glioma cells under hypoxia inhibits neutrophil AKT activity and suppresses anti-tumoral activities. Tsai HC*, Tong ZJ*, Hwang TL, Wei KC, Chen PY, Huang CY, Chen KT, Lin YJ, Cheng HW, Wang HT. Free Radic Biol Med. 2023 Jul 4;207:17-28. doi: 10.1016/j.freeradbiomed.2023.06.027. (*equal contribution)
2. Cigarette Smoke Containing Acrolein Contributes to Cisplatin Resistance in Human Bladder Cancers through the Regulation of HER2 Pathway or FGFR3 Pathway. Hong JH, Tong ZJ, Wei TE, Lu YC, Huang CY, Huang CY, Chiang CH, Jaw FS, Cheng HW, Wang HT. Mol Cancer Ther. 2022 Jun 1;21(6):1010-1019. doi: 10.1158/1535-7163.MCT-21-0725.
3. Acrolein plays a culprit role in the pathogenesis of diabetic nephropathy in vitro and in vivo. Tong ZJ, Kuo CW, Yen PC, Lin CC, Tsai MT, Lu SH, Chang YP, Liu WS, Tsou HH, Cheng HW, Wang HT. Eur J Endocrinol. 2022 Sep 22;187(4):579-592. doi: 10.1530/EJE-22-0493.
4. Acrolein induces mitochondrial dysfunction and insulin resistance in muscle and adipose tissues in vitro and in vivo. Jhuo JY, Tong ZJ, Ku PH, Cheng HW, Wang HT. Environ Pollut. 2023 Aug 23;336:122380. doi: 10.1016/j.envpol.2023.122380.