Neurosurgery, University of Maryland
Graeme F.Woodworth, MD, FACS is Professor and Chair of the Department of Neurosurgery and BioEngineering at the University of Maryland. He also serves as the Director of the Brain Tumor Program and the Translational Therapeutics Research Group in the Greenebaum Comprehensive Cancer Center at the University of Maryland School of Medicine. Dr. Woodworth completed medical school and neurosurgical residency training at Johns Hopkins. He also completed a post-doctoral fellowship in cancer nanomedicine at Johns Hopkins, where he worked closely with Dr. Suk. His clinical subspecialty areas of interest are Neurosurgical Oncology and Skull base and Stereotactic surgery. Dr. Woodworth’s research focuses on developing new therapeutic strategies to improve the treatments for brain-invading tumor cells, the cause of tumor recurrence in most brain cancers. These efforts include (1) leveraging the diverse interstitial effects of transcranial focused ultrasound and hyperthermia, (2) developing advanced nano-therapeutics to improve treatment efficacy, and (3) expanding the suite of patient-derived and genetically engineered models of human brain tumors to improve predictive therapeutic testing. A core component of the research has been centered on the concept of using the operating room as a portal for discovery and opportunity to improve our understanding of and therapeutic delivery to brain tumors. Dr. Woodworth’s team is leading the first-in-human clinical trials of focused ultrasound (FUS) mediated blood brain barrier opening in the United States, with the goal of using this localized delivery approach to advance nanomedicines for brain tumors.