St. Jude Children's Research Hospital
memphis, Tennessee, United States
Suzanne J. Baker, PhD is the Associate Director for Basic Research and Co-Leader of the Neurobiology and Brain Tumor Program at the St. Jude Children’s Research Hospital Comprehensive Cancer Center. She received her PhD degree in Molecular Biology and Human Genetics from The Johns Hopkins University, where she trained with Dr. Bert Vogelstein. After postdoctoral training with Dr. Tom Curran at the Roche Institute of Molecular Biology, she joined the faculty at St. Jude Children’s Research Hospital where she holds the Endowed Chair in Brain Tumor Research and is Director of the Division of Brain Tumor Research.
The Baker laboratory is focused on understanding the underlying molecular, cellular and genetic mechanisms driving high-grade gliomas, including diffuse intrinsic pontine glioma (DIPG) in children. Ongoing work in her laboratory evaluates genetic and epigenetic features of primary tumors and incorporates these genomic discoveries into the design and analysis of in vitro and in vivo models for mechanistic studies and preclinical testing. The unique genetic landscape of these tumors highlights critical connections between development, epigenetics and cancer.