Brigham and Women's Hospital/ Harvard Medical School
Boston, Massachusetts, United States
Dr. Chiocca is the Harvey Cushing Professor of Neurosurgery at Harvard Medical School and Chairman Neurosurgery at the Brigham and Women’s Hospital. He has been continuously funded by the NIH since 1996. He has more than 300 peer-reviewed publications. He has elucidated how viruses with specific gene mutations will replicate selectively in tumors with a specific defect in a tumor suppressor pathway. He has also shown how modulation of innate immunity will improve replication of these tumor-selective viruses. More recently, he has elucidated how specific microRNAs (mir128 and mir451) regulate cellular target transcripts to permit tumor cell self-renewal and invasion into brain. He has been PI of multi-institutional clinical trials of gene-, viral-therapies for malignant gliomas, has been permanent member of NIH study sections, of the recombinant DNA Advisory Committee (RAC/OBA) and of the NINDS Scientific Advisory Council. In 2013, he was vice-President of the Society for Neuro-Oncology (SNO). He was President of SNO (2015-2017) and President of the American Academy of Neurological Surgery (2018-2019). He is the current secretary of the American Association of Neurological Surgery. He also serves on the scientific advisory board of several foundations (Sontag, American Brain Tumor Association). He received The Grass Award in 2007, the Farber Award in 2008, the Bittner Award in 2013, the Joel A. Gingras Award in 2016 (ABTA) the Charles B. Wilson Career Achievement Award from the CNS/AANS Section on Tumors,2018 and the Victor Levin Award for Achievement in neuro-oncology (SNO, 2018). He was elected to the American Society for Clinical Investigation (2005), is an AAAS fellow (2005) and was also elected to the National Academy of Medicine (formerly Institute of Medicine) in 2014. He received . He also has served on multiple editorial boards and is the current Tumor Section Editor for Neurosurgery and Associate Editor for Neuro-oncology.