Severance Hospital, Yonsei University College of Medicine
Seoul, Seoul-t'ukpyolsi, Republic of Korea
I am a Professor currently working at Severance Hospital at Yonsei University, Seoul, Korea where I perform glioma-related surgery and translational research.
Selected recent publications (as corresponding author) of Seok-Gu Kang (ORCiD: https://orcid.org/0000-0001-5676-2037) (h-Index 38)
1. Lee JH, et al. Human glioblastoma arises from subventricular zone harboring low-level driver mutations. Nature. 2018 Aug; 560 (7717): 243-247.
2. Yoon SJ, et al. Glioblastoma cellular origin and the firework pattern of cancer genesis from the subventricular zone. J Korean Neurosurg Soc. 2020 Jan;63(1):26-33.
3. Park J, et al. Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program. Br J Cancer. 023 Oct;129(7):1061-1070
4. Yoon SJ, et al. Tissue Niche Miniature of Glioblastoma Patient Treated withNano-Awakeners to Induce Suicide of Cancer Stem Cells. Adv Healthc Mater. 2022 Sep 1;e2201586. doi: 10.1002/adhm.202201586.
5. Yoo KC, et al. Soluble ICAM-1 a pivotal communicator between tumors and macrophages, promotes mesenchymal shift of glioblastoma. Adv Sci (Weinh). 2022 Jan;9(2):e2102768.
6. Lim EJ, et al. Crosstalk between GBM cells and mesenchymal stem-like cells promotes the invasiveness of GBM through the C5a/p38/ZEB1 axis. Neuro Oncol. 2020 Mar; 22(10): 1452-1462.
7. Park J, et al. Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres. Neuro Oncol. 2018 Jun 18;20(7):954-965.
8. Kim EH, et al. Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin. Neuro Oncol. 2017 Feb; 19 (2): 197-207.
9. Yoo KC, et al. Proinvasive extracellular matrix remodeling in tumor microenvironment in response to radiation. Oncogene. 2018 Jun; 37 (24): 3317-3328.
10. Park J, et al. Transcriptome profiling-based identification of prognostic subtypes and multi-omics signatures of glioblastoma. Sci Rep. 2019 Jul 22;9(1): 10555.