Washington University School of Medicine
St. Louis, Missouri, United States
David H. Gutmann received his undergraduate, graduate (PhD) and medical (MD) degrees from the University of Michigan. Dr. Gutmann is the Donald O. Schnuck Family Professor, and directs the Washington University Neurofibromatosis Center.
His laboratory is focused on understanding the genomic, molecular and cellular basis for nervous system problems affecting children and adults with NF1 using both human induced pluripotent stem cells and novel genetically engineered mouse strains. They have used these preclinical models to define the cellular origins of tumors, immune regulation of cancer growth, neurons as drivers of neoplasia and growth, the impact of germline genetics on phenotypic expression, the role of sexual dimorphism in brain cell function and patient clinical outcome, and the major growth control pathways that dictate brain development in NF.
Dr. Gutmann has published over 500 peer-reviewed manuscripts, and his research laboratory has been continuous funded by the National Institutes of Health since 1993, including a National Institute of Neurological Disorders and Stroke R35 Research Program (MERIT) Award. In addition, he has been recognized for his achievements with numerous awards, including the 2012 Children’s Tumor Foundation Frederich von Recklinghausen Lifetime Achievement Award, a 2013 Washington University Distinguished Faculty Research Award, a 2017 Alexander von Humboldt Award, the 2019 Society for Neuro-Oncology Abhijit Guha Award, the 2020 National Neurofibromatosis Network Advocate of Hope Award, the 2020 American Academy of Neurology Neuro-Oncology Scientific Award, and the 2020 American Association of Neurology triennial George W. Jacoby Award. He is an elected Fellow of the American Academy of Neurology, the American Neurological Association, the Association of American Physicians, the American Association for the Advancement of Science, and the National Academy of Medicine, as well as a former member of the National Institute of Neurological Disorders and Stroke Advisory Council.
